Strain Name
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C57BL/6-Cd28tm1(CD28)Bcgen Ms4a1tm2(MS4A1)Bcgen/Bcgen
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Common Name
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B-hCD28/hCD20 mice
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Background
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C57BL/6
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Catalog number
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121253
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Related Genes
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CD28, CD28 molecule, Tp44;
CD20, MS4A1, membrane spanning 4-domains A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
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NCBI Gene ID
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12487,12482
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Protein expression analysis
Strain specific CD28 expression analysis in homozygous B-hCD28/hCD20 mice by flow cytometry.
Splenocytes were collected from WT and homozygous B-hCD28/hCD20 (H/H;H/H) mice, and analyzed by flow cytometry with species-specific anti-CD28 antibody. Mouse CD28 was detectable in WT mice. Human CD28 was exclusively detectable in homozygous B-hCD28/hCD20 but not WT mice.
Protein expression analysis
Strain specific CD20 expression analysis in homozygous B-hCD28/hCD20 mice by flow cytometry.
Splenocytes were collected from WT and homozygous B-hCD28/hCD20 (H/H;H/H) mice, and analyzed by flow cytometry with species-specific anti-CD20 antibody. Mouse CD20 was detectable in WT mice. Human CD20 was exclusively detectable in homozygous B-hCD28/hCD20 but not WT mice.