B-hCD3E/hTPBG mice
| Strain Name |
C57BL/6-Cd3etm2(CD3E)Bcgen Tpbgtm1(TPBG)Bcgen/Bcgen
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Common Name | B-hCD3E/hTPBG mice |
| Background | C57BL/6 | Catalog number | 112618 |
| Aliases |
CD3E, CD3epsilon, IMD18, T3E, TCRE, CD3 epsilon subunit of T-cell receptor complex; TPBG, 5T4, 5T4AG, M6P1, WAIF1, trophoblast glycoprotein
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Protein expression analysis
Strain specific CD3E expression analysis in homozygous B-hCD3E/hTPBG mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD3E/hTPBG mice (H/H; H/H), and analyzed by flow cytometry with species-specific anti-CD3E antibody. Mouse CD3E was detectable in WT mice (+/+). Human CD3E was exclusively detectable in homozygous B-hCD3E/hTPBG mice (H/H; H/H) but not in WT mice (+/+).
Strain specific analysis of TPBG expression in wild type (WT) mice and B-hCD3E/hTPBG mice by WB. Brain and spine were collected from wild type (WT) mice (+/+) and homozygous B-hCD3E/hTPBG mice (H/H; H/H), and analyzed by western blot with anti-TPBG antibody. Mouse TPBG was detectable in WT mice (+/+). Human TPBG was exclusively detectable in homozygous B-hCD3E/hTPBG mice (H/H; H/H).
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