B-hCTLA4/hIL2RA mice
| Strain Name |
C57BL/6-Ctla4tm1(CTLA4)Bcgen Il2ratm1(IL2RA)Bcgen/Bcgen |
Common Name | B-hCTLA4/hIL2RA mice |
| Background | C57BL/6 | Catalog number | 111851 |
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Related Genes |
CTLA4:CTLA-4; ALPS5; GRD4; CTLA4; CD; CD152; IDDM12; GSE; CELIAC3 IL2RA: p55; CD25; IL2R; IMD41; TCGFR; IDDM10 |
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Strain specific CTLA4 and IL2RA expression analysis in homozygous B-hCTLA4/hIL2RA mice by FACS. Splenocytes were collected from wild type (+/+) and homozygous B-hCTLA4/hIL2RA mice (H/H,H/H) stimulated with anti-mCD3ε antibody in vivo, and analyzed by FACS with species-specific anti-CTLA4 or anti-IL2RA antibodies. Mouse CTLA4 and IL2RA were detectable in wild type mice. Human CTLA4 and IL2RA were exclusively detectable in homozygous B-hCTLA4/hIL2RA mice but not in wild type mice.
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