B-hCTLA4/hTNFR2 mice
| Strain Name |
C57BL/6-Ctla4tm1(CTLA4)Bcgen Tnfr2tm1(TNFR2)Bcgen/Bcgen |
Common Name | B-hCTLA4/hTNFR2 mice |
| Background | C57BL/6 | Catalog number | 111843 |
| Aliases |
CTLA4:CTLA-4; ALPS5; GRD4; CTLA4; CD; CD152; IDDM12; GSE; CELIAC3 |
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Strain specific hCTLA4 expression analysis in homozygous B-hCTLA4/hTNFR2 mice by flow cytometry. Spleen was collected from wild-type mice (+/+;+/+) and homozygous B-hCTLA4/hTNFR2 mice (H/H; H/H), and analyzed by flow cytometry with species-specific anti-CD152 (CTLA4) antibody. Mouse CTLA4 was detectable in wild-type mice. Human CTLA4 was exclusively detectable in homozygous B-hCTLA4/hTNFR2 mice but not in wild-type mice.
Strain specific hTNFR2 expression analysis in homozygous B-hCTLA4/hTNFR2 mice by flow cytometry. Spleen was collected from wild-type mice (+/+;+/+) and homozygous B-hCTLA4/hTNFR2 mice (H/H; H/H), and analyzed by flow cytometry with species-specific anti-TNFR2 antibody. Mouse TNFR2 was detectable in wild-type mice. Human TNFR2 was exclusively detectable in homozygous B-hCTLA4/hTNFR2 mice but not in wild-type mice.
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