B-hDDR1 mice
| Strain Name |
C57BL/6-Ddr1tm1(DDR1)Bcgen/Bcgen
|
Common Name | B-hDDR1 mice |
| Background | C57BL/6N | Catalog number |
111121 |
|
Related Genes |
CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A | ||
Strain specific analysis of DDR1 gene expression in wild-type C57BL/6 mice and B-hDDR1 mice by RT-PCR. Mouse Ddr1 mRNA was detectable only in brain of wild-type C57BL/6 mice (+/+). Human DDR1 mRNA was detectable only in homozygous B-hDDR1 mice (H/H), but not in wild-type mice.
Strain specific DDR1 expression analysis in homozygous B-hDDR1 mice by western blot. Brain collected from wild-type C57BL/6 mice (+/+) and homozygous B-hDDR1 mice (H/H), and analyzed by western blot with DDR1 antibodies. Human DDR1 was exclusively detectable in homozygous B-hDDR1 but not in wild-type mice. Mouse DDR1 was detectable in wild-type mice. The DDR1 antibody is a human-specific antibody and the other is a human-mouse cross-recognition antibody.
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