B-hMERTK/hGAS6 mice
| Strain Name |
C57BL/6-Mertktm2(MERTK)Bcgen Gas6tm1(GAS6)Bcgen/Bcgen
|
Common Name | B-hMERTK/hGAS6 mice |
| Background | C57BL/6 | Catalog number |
112490 |
|
Related Genes |
Mertk (Me; Ny; Eyk; Mer; Nyk; nmf1; nmf12);Gas6 (AXSF; AXLLG) | ||
Protein expression analysis
Strain specific GAS6 expression analysis in homozygous B-hMERTK/hGAS6 mice by ELISA. Plasma was collected from wild-type mice (+/+) and homozygous B-hMERTK/hGAS6 mice (H/H), and analyzed by ELISA with species-specific GAS6 ELISA kit. Mouse GAS6 was detectable only in wild-type mice. Human GAS6 was detectable in homozygous B-hMERTK/hGAS6 mice but not in wild-type mice.
Strain specific MERTK expression analysis in homozygous B-hMERTK/hGAS6 mice by flow cytometry. Peritoneal washes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hMERTK/hGAS6 mice (H/H). Flow cytometry was analyzed with species-specific anti-MERTK antibody. Mouse MERTK was detectable in macrophage of wild-type mice. Human MERTK was only detectable in macrophage of homozygous B-hMERTK/hGAS6 mice but not in wild-type mice.
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