B-hTIM4/hTIM1 mice
| Strain Name |
C57BL/6-Timd4tm1(TIMD4)Bcgen Havcr1tm1(HAVCR1)Bcgen/Bcgen
|
Common Name | B-hTIM4/hTIM1 mice |
| Background | C57BL/6 | Catalog number | 110982 |
|
Aliases |
TIMD4 (TIM4; SMUCKLER) HAVCR1 (TIM; KIM1; TIM1; CD365; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1) |
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Strain specific TIM4 expression analysis in homozygous B-hTIM4/hTIM1 mice by flow cytometry. Macrophages in peritoneal lavage fluid were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hTIM4/hTIM1 mice (H/H), and analyzed by flow cytometry with species-specific anti-TIM4 antibody. Mouse TIM4 was detectable in wild-type mice. Human TIM4 was exclusively detectable in homozygous B-hTIM4/hTIM1 mice but not in wild-type mice.
Strain specific TIM1 expression analysis in homozygous B-hTIM4/hTIM1 mice by flow cytometry. Kidney tissue was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hTIM4/hTIM1 mice (H/H) stimulated with folic acid in vivo (5000 μg/mice, stimulation for 22 hours, i.p. ), and analyzed by flow cytometry with species-specific anti-TIM1 antibody. Mouse TIM1 was detectable in wild-type mice. Human TIM1 were exclusively detectable in homozygous B-hTIM4/hTIM1 mice but not in wild-type mice.
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