B-hTIM4 mice
| Strain Name |
C57BL/6-Timd4tm1(TIMD4)Bcgen/Bcgen
|
Common Name | B-hTIM4 mice |
| Background | C57BL/6 | Catalog number |
110837 |
|
Aliases |
SMUCKLER, TIM4 |
||
|
NCBI Gene ID |
276891 | ||
mRNA expression analysis
Strain specific analysis of TIM4 gene expression in wild-type C57BL/6 mice and B-hTIM4 mice by RT-PCR. Mouse TIM4 mRNA was detectable only in liver of wild-type C57BL/6 mice (+/+). Human TIM4 mRNA was detectable only in homozygous B-hTIM4 mice (H/H), but not in wild-type mice.
Protein expression analysis
Strain specific TIM4 expression analysis in homozygous B-hTIM4 mice by flow cytometry. Macrophages in peritoneal lavage fluid were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hTIM4 mice (H/H), and analyzed by flow cytometry with species-specific anti-TIM4 antibody. Mouse TIM4 was detectable in wild-type C57BL/6 mice. Human TIM4 was exclusively detectable in homozygous B-hTIM4 mice but not in wild-type C57BL/6 mice.
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