Strain Name
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BALB/c-Tnfrsf1btm1(TNFRSF1B)Bcgen/Bcgen
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Common Name
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B-hTNFR2 mice(C)
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Background
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BALB/cCrSlcNifdc
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Catalog number
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112644
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Aliases
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TNFRSF1B (Tumor necrosis factor receptor superfamily, member 1b)
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Protein expression analysis in T cells
Strain specific TNFR2 expression analysis in wild-type and B-hTNFR2 mice(C) by flow cytometry. Splenocytes were collected from BALB/c (+/+) and homozygous B-hTNFR2 mice(C) (H/H) stimulated with anti-mCD3ɛ antibody (7.5μg/mice, stimulation for 24 hours, i.p.), and analyzed by flow cytometry with species-specific TNFR2 antibody. Mouse TNFR2 was detectable in wild-type mice. Human TNFR2 was exclusively detectable in homozygous B-hTNFR2 mice(C).
Protein expression analysis in Tregs
Strain specific TNFR2 expression analysis in wild-type and B-hTNFR2 mice(C) by flow cytometry. Splenocytes were collected from BALB/c (+/+) and homozygous B-hTNFR2 mice(C) (H/H) stimulated with anti-mCD3ɛ antibody (7.5μg/mice, stimulation for 24 hours, i.p.), and analyzed by flow cytometry with species-specific TNFR2 antibody. Mouse TNFR2 was detectable in wild-type mice. Human TNFR2 was exclusively detectable in homozygous B-hTNFR2 mice(C).