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百奥赛图（北京）医药科技股份有限公司

百奥赛图公司介绍手册

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B-NDG mice

B-NDG mice-PDX

B-hCSF1/hCSF1R mice

B-hTNFA/hTNFR2 mice

B-hIL6/hIL6R mice

B-hIL17A/hIL17F mice

B-hIL23A/hIL12B mice

B-hIL12A/hIL12B mice

B-hIL4/hIL4RA mice

B-hTNFA/hIL17A mice

B-Tg(hSIGLEC7/hSIGLEC9) mice

B-hCD28/hTROP2 mice

B-hTSLP/hTSLPR mice

B-hPD-L1/hTIM3 mice

B-hPD-1/hB7-H3 mice

B-hPD-1/hCD39 mice

B-hOX40/h4-1BB mice

B-hTNFR2/hTNFR1 mice

B-hPVRIG/hTIGIT mice

B-hTWEAK/hAPRIL mice

B-hCD28/hCD20 mice

B-Tg(hLILRB1/hLILRB4) mice

B-Tg(hLILRB2/hLILRB3) mice

B-hOX40/hOX40L mice

B-hCD3E/h4-1BB mice

B-hBTLA/hHVEM mice

B-hCD3E/hCD20 mice

B-hPD-1/hTIM3 mice

B-hPD-L1/h4-1BB mice

B-hPD-L1/hCD40 mice

B-hPD-L1/hCD27 mice

B-hPD-L1/hCTLA4 mice

B-hCTLA4/h4-1BB mice

B-h4-1BB/h4-1BBL mice

B-hCTLA4/hGITR mice

B-hCD94/hNKG2A mice​

B-hPD-L1/hTIGIT mice

B-hPD-L1/hOX40 mice

B-hPD-1/hOX40 mice

B-hPD-L1/hLAG3 mice

B-hCTLA4/hOX40 mice

B-hCTLA4/hTIM3 mice

B-hPD-1/hBTLA mice

B-hPD-1/h4-1BB mice

B-hPD-1/hCD27 mice

B-hCTLA4/hLAG3 mice

B-hPD-1/hGITR mice

B-hPD-1/hCD40 mice

B-hCD3E/hCD28 mice

B-h4-1BB/hCD40 mice

B-hSIRPA/hCD47 mice

B-hCD40/hCD40L mice

B-hPD-1/hTIGIT mice

B-hCD3E/hIL2RA mice

B-hPD-1/hPD-L1 mice

B-hPD-1/hLAG3 mice

B-hPD-L1 plus/hCD47 MC38

B-hPD-1/hCTLA4 mice

B-hIL4/hIL4RA/hIL13 mice

B-hSIRPA/hCD47,Il2rg KO mice

B-hSIRPA/hCD47, Prkdc KO mice

B-hPD-1/hPD-L1/hIL2RA mice

B-hCD3EDG mice

B-hPD-1/hPD-L1/hGITR mice

B-hIL2/hIL2RA/hIL2RB mice

B-hLTA/hTNFA/hLTB mice

B-hCD3EDG/hCD28 mice

B-hCD3EDG/hTROP2 mice

B-hPD-1/hPD-L1/hTIM3 mice

B-hPD-1/hPD-L1/hC5AR1 mice

B-hPD-L1/hSIRPA/hCD47 mice

B-hPD-1/hSIRPA/hCD47 mice

B-hPD-1/hPD-L1/h4-1BB mice​

B-hPD-1/hPD-L1/hCTLA4 mice

B-hPD-1/hPD-L1/hTIGIT mice

B-hPD-1/hPD-L1/hLAG3 plus mice

B-hPD-1/hPD-L1/hTNFR2 mice

B-hPD-1/hLAG3/hTIM3 mice

B-hPD-1/hPD-L1/hCD40 mice

B-NDG nude mice

B-hPD-1/hPD-L1/hOX40 mice

B-NDG B2m KO mice plus

B-NDG hIL15 mice

B-NDG HLA-A2.1 mice

B-NDG hIL6 mice

B-hSIRPA/hCD47,Prkdc/Il2rg KO mice

B-NDG hTHPO mice

B-NDG hSIRPA mice

B-hPD-1/hPD-L1/hSIRPA/hCD47 mice

B-NDG hIL7/hIL15 mice

SITC2024: TAA antibody library and novel linker/payload BLD1102 for ADC, bispecific ADC and nanobody-drug conjugate development

SITC 2024: Establishing a tumor cell model to evaluate the bystander effect of antibody-drug conjugate (ADC) therapies

SITC 2024: A novel IL12Rβ1 and IL12Rβ2 humanized mouse model for preclinical efficacy and toxicity evaluation of human IL-12 analogs

SITC 2024: Humanized HER2-expressing tumor cells established syngeneic models for evaluating HER2 antibody-drug conjugate (ADC) therapy

SITC2024: The paring of CD200 humanized cancer cells with CD200 and CD200R double humanized mice for the preclinical evaluation of the combination of anti-human CD200 antibodies and immune checkpoint drugs

BCG014: A CDH3-Targeting ADC with a Novel TOPO1 Inhibitor Payload

World ADC San Diego2024: Development of a novel bispecific ADC targeting SEZ6 and B7H3 for small cell lung cancer (SCLC)

ESDR2024：BCG028, a novel Fc-optimized fully human biparatopic OX40 antagonist for treating atopic dermatitis

ASCO 2024: A phase II, multi-center, open-label study to evaluate the safety and efficacy of YH003 in combination with Toripalimab (anti-PD-1 mAb) in patients with unresectable/metastatic pancreatic ductal adenocarcinoma

IO Summit Europe 2024: Fully human conditional agonist 4-1BB×CD40 bispecific antibody exhibits potent in vitro and in vivo efficacy

Festival of Biologics 2024: Generation of a TAA Antibody Library to Support the Development of Antibody-Drug Conjugates (ADC)

AACR 2024: Identification of fully human CCR8 antibodies that demonstrate excellent ADCC function, potent blocking activity, and robust anti-tumor immune responses

AACR 2024: Targeting mutant KRAS proteins with novel TCR-mimic fully human antibodies

AACR 2024: BCG020, a novel bispecific antibody targeting EGFR and CD70, is effective against EGFR and CD70 high expressed tumors

AACR 2024: BCG016, a first-in-class bispecific antibody-drug conjugate targeting 5T4 and MUC1, demonstrates potent preclinical anti-tumor activity

AACR 2024: BCG017, a bispecific ADC targeting PTK7 and EGFR exhibits anti-tumor efficacy in PDX models

AACR 2024: A novel EGFR×HER3-targeting bispecific antibody drug-conjugate, BCG019, demonstrates robust anti-tumor efficacy in preclinical evaluation

AACR 2024: BCG022, a novel HER3×MET bispecific antibody-drug conjugate (bsADC), demonstrates promising anti-tumor efficacy

AACR 2024: A first-in-class bispecific ADC targeting FOLR1 and MUC1 exhibits promising anti-tumor activity in a FOLR1low xenograft model

AACR 2024: BCG033, a novel bispecific antibody-drug conjugate targeting PTK7 and TROP2, demonstrates preclinical efficacy against triple-negative breast cancer and other solid tumor xenografts

BIO KOREA 2025 | 百奥赛图将设立展台#H21并参与1对1约见交流

ARVO 2025｜百奥赛图与南京正大天晴合作开发TED创新疗法IGF-1R全人抗体研究成果亮相

百奥赛图圣地亚哥新办公室正式启用，加速全球化战略布局

World ADC London 2025 | 百奥赛图将展示两项创新ADC资产并进行主题演讲

百奥赛图将出席第43届摩根大通医疗健康年会及同期会议

百奥赛图宣布与SOTIO达成全人源抗体许可协议，用于开发治疗结直肠癌的新型ADC候选药物SOT109

百奥赛图宣布与育世博达成合作，推进双特异性抗体双药物偶联物（BsAD2C）研发

百奥赛图宣布Adcendo ApS行使抗体选择权以加速ADC开发

AET-US 2024｜百奥赛图将展示创新抗体发现平台海报并设立展台#212

百奥赛图再度荣获“最具价值医药及医疗公司”奖项，持续引领行业创新发展

百奥赛图宣布IDEAYA提名具有同类首创潜力的B7H3/PTK7拓扑异构酶抑制剂有效载荷双特异性ADC（IDE034）作为开发候选药物并行使选择权

SITC 2024｜百奥赛图将展示5张海报并设立展台

World ADC San Diego 2024| 百奥赛图将展示两项创新ADC资产并设立展台

BIO EUROPE 2024| 百奥赛图将设立展台并邀您进行1对1约见交流

百奥赛图将参展BioJapan 2024并做研讨会口头报告

“千鼠万抗”合作成果丰硕，解锁新型药物开发的高效选择

百奥赛图宣布与IDEAYA Biosciences就具有同类首创潜力的B7H3/PTK7拓扑异构酶抑制剂有效载荷双特异性ADC项目达成选择权和许可协议

SOTIO与百奥赛图达成多靶点抗体合作协议，扩大ADC产品管线

百奥赛图祝贺合作伙伴多玛医药双抗ADC DM001获得美国FDA IND批准

百奥赛图共轻链小鼠RenLite技术平台获美国专利授权

百奥赛图与印度代理商GVSAP就百奥动物业务签署战略合作协议

BIO 2024 | 百奥赛图邀您进行1对1约见交流

百奥赛图与BioCopy达成类TCR抗体评估与潜在授权协议

ASCO 2024 | 百奥赛图/祐和医药将公布YH003（CD40激动型单抗）两项临床II期研究数据

BIO KOREA 2024 | 百奥赛图将设立展台并参与1对1约见交流

海报下载丨百奥赛图与您分享AACR 20张海报研究成果，回顾展台亮点

百奥赛图将在IO Summit Europe 2024大会上展示全人双抗海报

百奥赛图抗体合作伙伴Syncromune在AACR做口头报告，展示SYNC-T™ SV-102的临床I期数据，结果积极

百奥赛图与ABL Bio达成合作，共同开发新型双抗ADC药物

邀请函 | 百奥赛图2023年度业绩电话会

BIO-Europe Spring 2024 | 百奥赛图邀您进行1对1约见

AACR 2024 | 百奥赛图将展示20张海报并设立展台，展示千鼠万抗和百奥动物业务重点产品最新进展

World ADC London 2024 | 百奥赛图将展示双抗ADC和即插即用TAA抗体库的最新进展

百奥赛图和吉利德达成多靶点抗体合作协议

百奥赛图成立子品牌千鼠万抗（RenBiologics），全人抗体分子和抗体发现平台加速全球新药研发

沈月雷博士接受Investment Reports/Newsweek采访

百奥赛图与Radiance Biopharma达成双抗ADC协议

百奥赛图YH008获授方微芯新域新一代肿瘤免疫双抗产品NWY001完成首例受试者入组

Manhattan BioSolutions与百奥赛图达成创新型抗体评估与潜在授权协议，用于靶向疗法

百奥赛图将出席第42届摩根大通医疗健康年会及同期会议

百奥赛图与乐普创一合作开发基于WT1类TCR抗体的多特异性T细胞连接器药物取得里程碑进展

百奥赛图与Neurocrine Biosciences达成多靶点抗体协议

百奥赛图与Ona Therapeutics达成抗体协议，用于针对实体瘤的ADC药物开发

百奥赛图荣获 “最具价值医药及医疗公司”奖项

百奥赛图全人抗体小鼠RenMab平台关键技术获得美国专利授权

AACR 2024: TIL analysis demonstrates different mechanisms underlying PD-1 resistance in animal models

CNS Drug Delivery Summit 2023 | 百奥赛图全人TFR1重链抗体成功将药物载荷递送入脑

AACR 2024: Generation of a novel severely immunodeficient Sprague Dawley rat model for xenograft studies

SITC 2023精彩回顾 | 一网打尽百奥赛图16张海报亮点

AACR 2024: A novel humanized NKP46 mouse model to support xenograft studies evaluating NK cell-based cancer immunotherapies

BIO-EUROPE 2023 | 百奥赛图将设立展台，展示新药资产及全人药物发现平台

AACR 2024: A novel humanized CD16A model to evaluate efficacy of human antibody therapeutics in triggering ADCC

SITC 2023 | 百奥赛图将展示16张海报并设立展台

AACR 2024: Development and validation of humanized HLA mouse model platforms for preclinical evaluation of novel peptide vaccines

百奥赛图/祐和医药将在ESMO 2023公布YH003（CD40单抗）I期临床研究完整数据

AACR 2024: Establishment of a humanized IL5/IL5RA mouse model to evaluate modulators of eosinophilic inflammation in vivo

World ADC San Diego 2023 | 百奥赛图将展示两张双抗ADC海报并设立展台

AACR 2024: Development of humanized VEGFA models to assess preclinical efficacy of novel therapeutics in vivo

百奥赛图将参展BioJapan 2023并做研讨会口头报告

AACR 2024: Validation of humanized TL1A mice for advancing preclinical research

百奥赛图专有CD3E及CD3EDG人源化小鼠动物模型助力T细胞靶向药物研发

AACR 2024: Establishment of humanized CD3EDG/4-1BB mice for testing novel T cell engagers

RenMice系列全人抗体/TCR小鼠彰显百奥赛图在生物药开发领域的创新能力

AACR 2024: Generation of humanized PD-1/PD-L1/CD94/NKG2A mice for evaluating novel combination therapies

百奥赛图与Myricx达成抗体评估、选择与授权协议，用于ADC药物开发

AACR 2024: Generation and validation of a novel humanized IL-31/IL-31RA/OSM/OSMR mouse model

百奥赛图全资子公司祐和医药与美国Syncromune公司就YH002 （OX40单抗）等达成技术转移协议

CNS Drug Delivery Summit 2023: Discovery of RenNano-derived human TFR1 HCAbs that can efficiently cross the blood-brain barrier and deliver payload

一图读懂 | 百奥赛图2023上半年业绩亮点

百奥赛图升级两大业务线，推出子品牌BioMice百奥动物，赋能全球创新药物研发

新药研发经理

海外业务增长迅猛，百奥赛图波士顿公司入住新址

“千鼠万抗”按计划实现重要里程碑进展，百奥赛图抗体业务进入快速收获期

药理学科学家

SITC 2023: BSA01, a bsADC targeting EGFR and membrane-bound MUC1-C, exhibits anti-tumor efficacy in vivo

百奥赛图与Pheon Therapeutics达成授权协议

研发科学家—未来研究院

SITC 2023: BCG022: A HER3×MET Bispecific Antibody-drug Conjugate (BsADC) Targeting Key Mechanisms of Bypass Resistance in Multiple Tumor Types

百奥赛图全人抗体小鼠RenMab平台关键技术获得中国专利授权

SITC 2023: A novel bsADC targeting PTK7 and TROP2, BCG033, demonstrates preclinical efficacy against triple-negative breast cancer xenografts

百奥赛图将在IO Summit Europe大会上展示双抗ADC海报

动物模型开发研究员

SITC 2023: Identification of fully human TCR-mimic antibodies targeting the KRAS G12V/HLA complex generated in HLA-transgenic RenMab mice

百奥赛图旧金山办公室成立，加速公司业务的全球布局

项目方案负责人

SITC 2023: Preclinical Application of a Fully Human TCR-mimic Antibody Developed to Target NY-ESO-1/HLA-A02

百奥赛图将在BIO 2023大会上展示管线资产和“千鼠万抗”进展

抗体发现研究员

SITC 2023: Fc-Competent Fully Human Anti-TIGIT Blocking Monoclonal Antibodies Demonstrated Potent Anti-Tumor Efficacy in Preclinical Models

在第70届日本实验动物学会年会（JALAS）与百奥赛图亚太商务团队见面！

SITC 2023: Development of a Preclinical CD98HC Mouse Model for Therapeutic Studies

百奥赛图将于BIO KOREA 2023大会设立展台并参与1对1约见交流

抗体表征分析研究员

SITC 2023: Generation and Validation of Humanized GARP/TGFB1 Mice for Testing Novel Anti-human GARP Antibodies

AACR 2023 | （内含海报下载链接）百奥赛图展示了16项抗体药物资产与平台，9个临床前动物模型，并设立展台

YH012

蛋白工程研究员

SITC 2023: Humanized CD200/CD200R Mice as a Tool for Evaluating Novel Therapeutics

聚智·开放 共享新药新时代 | 第九届海门会议精彩内容回顾

SITC 2023: Humanized ICOS Mice as a Novel Tool for Predicting and Monitoring T-cell-mediated Immunotherapy Response

YH015

一图读懂 | 百奥赛图2022年度业绩

B-hFcRn mice

沈月雷

体外细胞功能分析研究员

SITC 2023: Humanized NKP46 Mouse Models for Testing Novel NK Cell-based Immunotherapies

YH016

晚间专场丨新形势下的投资与创业逻辑

郭朝设

SITC 2023: Preclinical CD3-based Mouse Models for Evaluation of Bi-specific T-cell Engager Antibodies

YH017

邀请函 | 百奥赛图2022年度业绩电话会

BCG003

杨毅

SITC 2023: A Novel B2m-deficient Immunodeficient Model Expressing Human IL15 for Preclinical Evaluation of T Cell and NK Cell-based Therapies

BCG008

百奥赛图将参加BIO-EUROPE SPRING 2023大会并进行1对1约见

百奥赛图宣布与杨森达成RenLite授权协议

YH008双特异性抗体药物获中国NMPA批准进入临床试验

刘斌

【重磅嘉宾公布】4月齐聚百奥赛图海门会议，共享新药新时代！

BCG005

王永亮

百奥赛图携最新双抗ADC管线亮相World ADC London大会

BCG007

百奥赛图全资子公司祐和医药与微芯生物控股公司微芯新域就YH008双特异性抗体达成大中华区授权协议

BCG010

BCG006

百奥赛图宣布启动“Nano 100计划”，开发针对100+靶点的全人治疗性纳米抗体

百奥赛图与翰森制药签署全人抗体许可协议

BCG013

百奥赛图将出席JPM大会及同期会议，创新平台与药物资产加速走向全球

百奥赛图自研双抗获FDA批准进入临床试验

百奥赛图与ADC Therapeutics签署抗体协议

百奥赛图成功研发全人纳米抗体小鼠RenNano，重塑纳米抗体药物研发格局

百奥赛图全资子公司祐和医药与TRACON共同宣布YH001（CTLA-4单抗）联合恩沃利单抗（PD-L1）和化疗一线治疗软组织肉瘤完成首例患者给药

百奥赛图将在SITC 2022大会上设立展台

百奥赛图将在PEGS EUROPE 2022大会上展示RenLite平台、类TCR抗体平台和两项药物资产

李镝锐

百奥赛图将于ChinaBio合作论坛展示管线资产和五大全人抗体发现技术平台的最新进展

百奥赛图全资子公司祐和医药与韩国ISU ABXIS开展基于YH003序列开发三特异性抗体的药物合作开发

百奥赛图全资子公司祐和医药与美国Syncromune公司就OX40单抗（YH002）等达成全球授权协议，共同开发瘤内免疫疗法

百奥赛图将在BIO-EUROPE 2022大会上展示临床前及药物临床开发资产

IWHM6 | 百奥赛图将展出12张创新型大/小鼠模型海报

张海超

BioJapan2022 | 百奥赛图将携创新型新药研发平台、双抗ADC项目和管线进展亮相

一图读懂 | 百奥赛图2022上半年业绩亮点

百奥赛图与中科奥格达成CD40抗体抑制剂在异种器官移植领域的合作

邀请函 | 百奥赛图2022年中期业绩电话会

【祝贺】百奥赛图再次荣登“2021年度中国抗体药物企业创新力TOP30排行榜”

姚佳维

百奥赛图入选“2022中国医药创新企业100强”榜单（第二梯级）

百奥赛图与泛恩生物达成基于类TCR抗体的细胞治疗药物开发合作

百奥赛图在港交所主板上市，立志成为全球新药发源地

百奥赛图与TRACON共同宣布YH001（CTLA-4单抗）联合PD-L1单抗一线治疗软组织肉瘤的临床试验申请获FDA批准

百奥赛图将携手SABPA于圣地亚哥举办抗体及ADC药物研发讨论会

百奥赛图将携RenLite平台和双抗ADC管线亮相WAC2022

百奥赛图深化与默克合作

百奥赛图荣登《麻省理工科技评论》“50家聪明公司”榜单

百奥赛图与LiberoThera共同开发全人GPCR抗体药物取得里程碑式进展

YH003（CD40单抗）联合PD-1单抗和白蛋白紫杉醇一线治疗黏膜型黑色素瘤的中国II期临床试验完成首例患者给药

【倒计时3天】7月2日相聚线上海门会议，共同开拓新药新格局！

企业荣誉 · 2022未来医疗100强｜百奥赛图荣获“中国创新生物医药榜TOP100”

完整日程丨7月2日第八届百奥赛图海门会议，“云端”同样精彩！

百奥赛图欧洲创新中心将出席2022年欧洲抗体工程与治疗峰会

百奥赛图将携12项产品管线，300+早期项目及5大全人抗体技术平台亮相BIO2022

百奥赛图/祐和医药将在2022年美国临床肿瘤学会（ASCO）年会上公布其CD40单抗与CTLA-4单抗的最新临床研究数据

百奥赛图与默克签署抗体协议

百奥赛图/祐和医药宣布其CD40单抗YH003联合CTLA-4抗体YH001和PD-1单抗的澳洲I期临床研究完成首例患者给药

AACR2022丨百奥赛图将公布多项创新药研究进展及创新模型临床前研究数据

RenMice 手册

百奥赛图欧洲创新中心在德国海德堡成立，国际化进程加速

百奥赛图与乐普创一达成基于类TCR抗体的多特异性抗体药物开发合作

延期通知 | 关于第八届百奥赛图模式动物与医药产业大会延期举行的通知

ESMO2023: Phase I open-label, dose escalation and expansion study of YH003 in combination with Toripalimab in patients with advanced solid tumors

精彩纷呈 | 4月16日海门会议，一起开拓新药新格局！

百奥赛图与百济神州达成关于RenMab/RenLite全人抗体小鼠授权使用的合作

百奥赛图/祐和医药宣布其OX40抗体YH002联合其CTLA-4抗体YH001的全球多中心I期临床研究于澳洲完成首例患者给药

AACR 2023: A First-In-Class Anti-HER2/TROP2 Bispecific Antibody-Drug Conjugate (YH012) Exhibits Potent Anti-Tumor Efficacy

百奥赛图与南京正大天晴签署全人抗体合作开发协议

抗CD40、抗CTLA-4和抗PD-1单抗三药联合I期临床试验获得中国国家药品监督管理局批准

AACR 2023: A Novel EGFR x MUC1 Bispecific Antibody-Drug Conjugate, BSA01, Targets MUC1 Transmembrane Cleavage Products and Improves Tumor Selectivity

新一代治疗性抗体--双抗ADC药物研发平台

AACR 2023: BCG022: A Novel Bispecific Antibody-Drug Conjugate Targeting HER3 and MET

上线啦丨百奥动物BioMice专属网站首发上线，pick蓝宝共度情人节

AACR2023:Discovery of BCG033, A Novel Anti-PTK7xTROP2 Bispecific Antibody-Drug Conjugate with Promising Efficacy Against Triple-Negative Breast Cancer

百奥赛图与荣昌生物进一步拓展抗体药物开发领域的深度合作

百奥赛图与星奕昂达成免疫细胞治疗药物开发战略合作

新药资产手册

宠物肿瘤转化医学平台项目竣工环境保护验收监测报告信息公开

百奥赛图抗体研发实验室项目竣工环境保护验收监测报告信息公开

【首轮预告】第八届百奥赛图模式动物与医药产业大会 ——聚焦源头创新，开拓新药新格局

百奥赛图年度回顾 | 蓄力一纪，再启新程

百奥赛图全资子公司祐和医药宣布其CD40抗体YH003联合PD-1抗体的国际多中心II期临床研究完成首例患者给药

AACR 2023: RenNano® Mice: A Heavy-Chain-Only Antibody Platform for the Generation of Nanobody Therapeutics

百奥赛图全资子公司祐和医药宣布其抗4-1BB抗体YH004的澳洲I期临床研究完成首例患者给药

AACR 2023: Discovery of RenNano®-Derived Human Heavy-Chain-Only Antibodies That Cross the Blood-Brain-Barrier

百奥赛图全资子公司祐和医药抗CTLA-4单抗YH001二期国际多中心临床试验获中国国家药品监督管理局批准

AACR 2023: Targeting Intracellular Tumor Antigens Using Fully Human TCR Mimic Antibodies Derived From HLA Transgenic RenMice

百奥赛图全资子公司祐和医药抗CD40单抗YH003二期国际多中心临床试验获中国国家药品监督管理局批准

AACR 2023: The RenMice HiTS (Hyperimmune Target Specific) Platform Facilitates Identification of Novel Therapeutic Antibodies for Challenging Targets

百奥赛图喜获2021中国生物医药产业链创新风云榜--标杆奖

可持续发展

AACR 2023: 1C3, A Novel Non-Blocking Anti-Human TNFR2 Antibody, Promotes Effector T Cell Responses and Demonstrates Potent Anti-Tumor Activity

技术为源，创新不止 | 点开视频，带你了解“百奥动物”

公益活动

AACR 2023: *Novel Preclinical Candidates Targeting B7-H3, 6B5 and 10F7, Are Suitable for Development Into Various Drug Modalities

百奥赛图及其全资子公司祐和医药与TRACON达成合作，推进YH001治疗软组织肉瘤等适应症在北美的临床开发及商业化

生命健康

AACR 2023: BCG008, A Human Siglec-15 Blocking Antibody, Displays Potent Anti-Tumor Activity in Siglec-15-Humanized Mice

百奥赛图携手Envigo共同推进重度免疫缺陷B-NDG小鼠销售

企业员工

双抗及双抗ADC手册

AACR 2023: D02, A Novel, Non-Blocking Antibody Targeting IL2RA, Exhibits Significant Anti-Tumor Activity in IL2RA-Humanized Mice

祐和医药宣布其CD40中国I期临床研究完成首例患者用药

AACR 2023: A Novel Triple Humanized B-hPD-1/hPD-L1/hCCR8 Mouse Model to Evaluate In vivo Efficacy of Combination Therapies

祝贺丨荣昌生物RC118首获澳洲临床试验许可！百奥赛图合作RC118抗体

AACR 2023: B-hCD94/hNKG2A Mice Provide a Preclinical Tool for Evaluating Therapeutic Antibodies Targeting Human NKG2A

百奥赛图与华润生物医药达成针对多个靶点抗体药物开发全面战略合作

AACR 2023: Generation of Humanized TREM2 Mice for Preclinical Evaluation of Therapeutics Targeting Tumor-Associated Macrophages

百奥赛图/祐和医药YH001和YH003二期临床试验双双获得FDA批准

AACR 2023: Humanized OX40/OX40L Mice as a Tool for Evaluating Novel Therapeutics

11月3-4日 ▏百奥赛图受邀参加第二届DJSeedin创新合作峰会！

百奥赛图宣布完成数千万美元新一轮融资，全力打造抗体新药研发引擎

AACR 2023: In vivo Efficacy Evaluation of Anti-Human VEGFR2 Antibodies in Humanized B-hVEGFR2 Mice

对话实录丨投资大佬与创业老将穿越中国医药20年的经典圆桌

百奥赛图与星亢原就共同开发生物大分子创新药达成战略合作

AACR 2023: In vivo Efficacy of an Anti-Human IL11RA Antibody in B-hIL11RA Mice With APAP-Induced Liver Damage

聚焦源头创新丨第八届海门会议精彩内容回顾-2

聚焦源头创新丨第八届海门会议精彩内容回顾-1

AACR 2023: Novel Humanized CD36 Mouse Model for Therapeutic Studies

7月29-30日 ▏百奥赛图受邀参加XDC及多抗新型药物全球创新峰会！

祐和医药宣布任命陈兆荣博士担任首席医学官

祐和医药将在2021 ASCO年会公布YH001 （抗CTLA-4单抗）和YH003（抗CD40单抗）的临床进展数据

YH001

AACR 2023: Development of Immunodeficient Mice Expressing Human IL3, GM-CSF, CSF1 and THPO for Improved Human Myeloid and Lymphoid Cell Reconstitution

【相约2.22】探索双靶点ADC新药开发新格局

祐和医药CD40抗体获中国国家药品监督管理局批准临床

AACR 2023: Development of MHC I/II Knock-Out Immunodeficient Mouse Strains for Alleviating GvHD Induced by Human PBMC Reconstitution

上线啦丨百奥动物专属网站首发上线，pick蓝宝共度情人节

【完整会议日程】丨5月14-16日第七届百奥赛图模式动物与医药产业大会

YH001

2021 CSCO | 祐和医药将公布YH001（抗CTLA-4单抗）的多项最新药物临床开发进展数据

AACR2021丨 百奥赛图公布双抗药物YH008数据，展示16篇临床前研究海报

YH002

合成生物学研究员

创药蓝海丨 Join us 一起乘风破浪

百奥赛图与多禧生物开展抗肿瘤抗体偶联药物开发战略合作

YH003

靶点生物学研究员

【学术沙龙-北京·成都站】 “百奥动物”与“千鼠万抗”加速生物医药研发

百奥赛图与信达生物达成关于RenMab全人源抗体鼠模型授权使用的合作

YH003

百奥赛图2021年系列学术沙龙 “百奥动物”与“千鼠万抗”加速生物医药研发

百奥赛图与君实生物达成关于RenMab小鼠授权使用的合作

YH003

PEGS-EU 2022:YH013, A Fully-human EGFR x MET Bispecific ADC Exhibits Outstanding Specificity and Anti-tumor Eff­icacy

Scientist,R&D

ADC药物研发科学家

夏日暖洋洋，C位小鼠促销忙——B-NDG小鼠宠粉季火热来袭！

体内药效学研究

百奥赛图和日本Ina Research达成动物模型销售及临床前药理药效服务日本地区代理协议

PEGS-EU 2022:1C3—A Differentiated Non-Blocking Agonist TNFR2 Antibody for Cancer Immunotherapy

【Webinar】Everybody's Soulmate in the Antibody World?

百奥赛图江苏基因生物技术有限公司

体外药理学研究

百奥赛图和美国Xencor达成关于RenMab/RenLite 的授权使用合作

YH004

PEGS-EU 2022:A Novel TCR-mimic Fully Human Antibodies Discovery Platform

百奥赛图（上海）医药科技有限公司

百奥赛图与盟科药业就共同推进抗感染创新生物药达成战略合作

PK/PD

平等

至本医疗与百奥赛图达成战略合作，共同推进新靶点抗肿瘤药物的开发

YH008

B-DIO mice

World ADC San Diego2022丨YH013, a fully-human EGFR x MET bispecific ADC exhibits outstanding specificity and anti-tumor efficacy

Biocytogen Europe Innovation Center

【BioMice礼上网来】谁是zui牛小鼠，Get专“鼠”豪礼

全人抗体小鼠授权

生物标记(Biomarker)

责任

百奥赛图与日本LiberoThera达成战略合作协议

BCG011

ASCO 2022: A phase I open-label dose escalation of YH003 (CD40 mAb) in combination with toripalimab (PD-1 mAb) in patients with advanced solid tumors

B-ob/ob mice

B-F9 KO mice

B-F8 KO mice

B-Apoe KO mice

B-p53 KO mice

B-Igh-J KO mice

百奥赛图（南通）新药创制基地启动暨百奥动物（BioMice）品牌发布会

B-NDG hSIRPA/hCD47 mice

百奥赛图人源化小鼠模型登录国际顶级期刊

Biocytogen Boston Corp.

毒理学研究

团结

药物合作开发

YH013

RenLite

BCG009

ASCO 2022: A first-in-human phase I dose escalation of YH001 (CTLA-4 mAb) in combination with PD-1 mAb in patients with advanced solid tumors

B-Il2rg KO rats

B-SDG rats

B-Rag2 KO rats

B-Pink1 KO rats

B-Apoe KO rats

B-Ldlr KO rats

B-Apoa4 KO rats

B-p53 KO rats

B-NDG hCSF1/hTHPO mice

祐和医药宣布其CTLA-4联合君实生物PD-1在澳洲I期临床取得突破性结果

【邀请函】第七届百奥赛图模式动物与医药产业大会 ——合作创新，突破新药开发困境

组织病理学研究

创新

多种灵活合作方式

B-hHGF/hMET mice

B-hNKC/hKIR mice

B-hNKC mice

B-hKIR mice

B-hLGALS1 mice

B-hOX40 mice(C)

B-hLTA/hTNFA/hLTB/hTNFR2/hTNFR1/hLTBR mice

B-hLIV-1 mice

B-hHLA-DRB1*7.1 mice

B-hHLA-DRB1*4.1 mice

B-NDG MHC I/II DKO/hB7-H3 mice

B-hIGF1R mice plus

B-hTFR1/hDMPK mice

B-NDG hCRBN mice

B-Bcrp KO rats

B-Mdr1 KO rats

B-hCLEC9A mice

B-hTL1A/hDR3 mice

2025 年百奥赛图 BioX 创新论坛邀请函

B-NDG MHC I/II DKO/hMSLN/hB7-H3 mice

B-Acat1 KO mice

B-OX2R KO mice

B-OX1R KO mice

B-hPNPLA3*I148M mice

B-hTGR5 mice

B-hCXCL16hCXCR6 mice

B-hCD3E/hCD22 mice

B-Tg(hVEGFA) mice

B-hDMD(exon44-46, del45) mice

B-hNOTCH3 mice

B-hPTK7 MC38

B-hSIGLEC6 mice

B-hDR3 mice

B-hIL20RA mice

B-hCD98HC rats

B-HLA-A11.1/hKRAS*G12V MC38

B-hSIGLEC15 mice(C)

B-hTL1A, Rag2 KO mice

B-hCD20/hCD22 mice

B-hCD20/hCD38 mice

B-hCD22/hCD38 mice

B-hTL1A/hLIGHT mice

B-hPD-1/hPD-L1/h4-1BB mice(C)

B-hPSGL-1, Rag2 KO mice

B-hCD19/hCD20 mice

B-hPD-1/hPD-L1/hLAG3 plus/hCD8 mice

B-hPD-1/hLAG3 plus/hCD8 mice

B-hMASP2/hTWEAK/hAPRIL mice

B-hFcRn, Ces1c KO mice

B-hFcRn, Ces1c KO mice(CB-17 SCID)

B-hGIPR/hGCGR mice

B-hGIPR/hGLP1R plus mice

B-hGCGR/hGIPR/hGLP1R plus mice

B-hASPH mice

B-hPRL mice

B-hCD3EDG mice(C.B6)

B-NDG hEPCAM mice

B-hCIDEB mice

B-hBMP10 mice

B-hIGF1 mice

B-hTROP2 rats

B-hL1CAM mice

B-hCD47/hGPC3 MC38

B-HLA-A11.1 MC38

B-HLA-A11.1/hKRAS*G12D MC38

B-HLA-A2.1/hAFP MC38

B-hRHO*P23H mice

B-hITGA2B mice

B-hGLP1R mice plus

B-hCD3EDG/hBAFFR mice

B-hCD3EDG/hCD28/hCD19 mice

B-hCD3EDG/hCD28/hCD38 mice

B-hCD3EDG/hCD28/hBCMA mice

B-hCD3EDG/hCD28/hGPRC5D mice

B-hTL1A/hDR3/hTNFA/hTNFR1/hTNFR2 mice

B-hIL17A/hIL17F/hIL17RA/hIL17RC mice

B-hIL33/hST2 mice

B-hSIRPA/hCD47/hEGFR mice

B-hHGF/hMET/hFcRn mice

B-hRNF43 mice

B-hPTH1R mice

B-hIL23R/hIL12RB1 mice plus

B-hCFB mice plus

B-NDG Fah KO mice

B-hAPOB mice

huHSC-B-NDG hIL15, FcγR KO mice

B-hCCR4/hCCL17 mice

B-hCD3EDG/hIgE/hFCER1A mice

B-hCD3EDG/hFOLR1/hFOLR2 mice

B-FcRn KO mice(CB-17 SCID)

B-Agtr1 KO rats

B-Asgr1 KO mice

B-Khk KO mice

B-Cd7 KO mice(C)

B-hCD3EDG/h4-1BB mice(C.B6)

huPBMC-B-NDG MHC I/II DKO mice plus

B-hTFR1/hCD98HC mice

B-hCD8/hCD19 mice

BCG012

B-hCD16A mice plus

B-hIL21R mice(C)

B-hDMPK mice

B-hPD-L1 mice plus

B-hKLKB1 mice

B-hTFR1 rats

B-hFcRn rats

B-hSCUBE2 mice

B-hPD-1/hBTLA/hHVEM mice

B-Mdr1/Bcrp KO mice

B-Mdr1/Bcrp KO rats

B-hGCGR/hGIPR/hGLP1R mice

B-hGIPR/hGLP1R mice

B-hIL13/hTSLP/hTSLPR plus mice

B-hIL13/hIL13RA1 mice

B-hPLVAP mice

B-HLA-A2.1/hGP100 MC38

B-hFcRn, Rag2 KO mice

B-hCD155,Rag2 KO mice

B-hADGRE5 mice

B-NDG hGPC3 mice

B-hITGB2 mice

B-NDG hHER3 mice

B-hCCL17 mice

B-hEPHA2 mice

B-H11-hINV-(HPV16 E6/E7/E5)x2 mice(FVB)

B-hPROKR2 mice

B-hLPA/hAPOB mice

B-hKLRG1 mice plus

B-hCD300E mice

B-hAGTR1 rats

B-Psen1*M146L*E120K mice

B-Psen1*P117L mice

B-NDG MHC I/II DKO/hMSLN mice

B-NDG hTROP2 mice

B-hMIF/hDDT mice

B-hFGF4 mice

B-hIL2/hIL2RA/hIL2RB/hIL2RG/hIL15/hIL15RA mice

B-hTNFRSF21 mice

B-hKHK mice

B-hHLA-DRB1*4.1 mice(C)

B-hHLA-DRB1*1.1 mice(C)

B-hGDF15 MC38

B-hCD74 mice

B-hSLC29A2 mice

B-Ldlr KO mice

B-hKREMEN2 mice

B-hSTAB1 mice

B-hCD31 mice

B-hRXFP1 mice

B-hPLAT mice

B-hHTR3A mice

B-hTFR1/hGDF8 mice

B-hTFR1/hEGFR mice

B-hCD98HC/hEGFR mice

B-hLPA plus/hAPOB mice

B-hCDH3/hCDH17 mice

B-hNECTIN4/hTROP2 mice

B-hSIRPA/hCD47,Apoe KO mice

B-hLPA/hAPOB/hPCSK9 plus mice

B-hTL1A/hDR3/hIL23A/hIL12B mice

B-hTL1A/hDR3/hα4β7 mice

B-hCD3EDG/hPSMA mcie

B-hCD3EDG/hCD19 mice(C.B6)

B-hCD3E/hCD19 mice(C)

B-hCD3EDG/hCD20/hBCMA mice

B-hCD20/hBCMA mice

B-hPD-1 plus/hPD-L1/hCD3EDG mice

B-hCD3EDG/hDLL3 mice

B-hCD3EDG/hCD33 mice

B-hCD3E/hCD39 mice

B-hCD3EDG/hTPBG mice

B-hCD3EDG/hCD20/hCD22 mice

B-hCD3EDG/h4-1BB/hCD19 mice

B-hCD3E/hHLA-DPA1*2.2/hHLA-DPB1*3.1 mice

B-hCD19/hCD79B mice

B-hCD3E/hB7-H3/hDLL3 mice

B-Pah KO mice

B-Dmd KO(del45-50) mice

B-hTFR1, Rag2 KO mice

B-hTFR1, Ids KO mice

B-hTMPRSS6 mice

B-hCCN2 mice plus

B-hMASP2 mice ad

B-hADAMTS4 mice

B-hIL1A mice

B-Coro1a KO mice

B-Gjd2 KO mice

B-hLPA/hANGPTL3 plus mice

B-hIL2RB/hIL2RG/hIL15/hIL15RA/hNKG2D plus mice

B-Pten flox mice

B-Apc flox mice

B-hCD79A/hCD79B mice

B-hGAST mice

B-hGP1BA mice

B-Ifnar1 KO mice(129S2)

B-hC5 mice

B-hHER3 rats

B-hHLA-DPA1*2.2/hHLA-DPB1*3.1 mice

B-hFLT3 mice

B-hIL1R1 mice

B-hIL12RB1/hIL12RB2 mice plus

B-NDG hF3 mice

B-hFCRL1 mice

B-hNTS mice

B-hMC5R mice

B-hPOMC mice

B-hPD-1 plus/hIL12RB1/hIL12RB2 mice

B-hNOTUM mice

B-hCMTM6 mice

B-hALB plus/hFcRn mice

B-Cd5 KO mice(C)

B-NDG FcγR KO mice

B-hPD-1/hPD-L1/hSIRPA/hCD47,Tg(hLILRB2/hLILRB3) mice

B-hPERP mice

B-hSERPINA1*E342K mice

B-hMASP2 rats

B-hCD83 mice

B-HLA-A2.1 MC38

B-hCD98HC/hTAU mice

B-hFSTL1 mice

B-hANXA1 mice

B-hFIX mice

B-hSERPINH1 mice

B-hSCG3 mice

B-hLRG1 mice

B-NDG hTHPO/hSCF mice

B-hCD98HC/hFcRn mice

B-hTFR1/hFcRn mice

B-hCD5/hCD19 mice

B-hPD-1 plus/hTNFA mice

B-hCD3EDG/hEPCAM mice

B-hPD-1 plus/hCCR9 mice

B-hVSIG4/hLAIR1 mice

B-hTAU*P301S mice

B-hTFR1/hTAU*P301S mice

B-hTFR1/hTAU mice

B-hCD98HC/hTAU*P301S mice

B-hSAS1B mice

B-hADAM28 mice

B-Tg(hCEACAM3/hCEACAM5/hCEACAM6/hCEACAM7) mice

B-hSULF-2 mice

B-hITGA3 mice

B-HLA-A2.1/hMAGEA4 MC38

B-HLA-A2.1/hWT1 MC38

B-hTL1A/hIL23A/hIL12B mice

B-Fabp4-iCre mice

B-hCD164 mice

B-Ifngr1 KO mice(129S2)

B-hGPR171 mice

B-hFGFR4 mice

B-hC1S mice

B-hIL13RA2 mice

B-hDCIR mice

B-hKISS1 mice

B-hSIGLEC1 mice

B-hAPCDD1 mice

B-hTRPM4 mice

B-hBMP9 mice

B-hCD11B mice

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B-hGNRHR mice

B-hSAA1 mice

B-hMPL mice

B-hGPR65 mice(C)

B-hNINJ1 mice

B-hPGF mice

B-NDG hCSF1 mice

B-hIL4/hIL4RA/hTSLP/hTSLPR mice(C.B6)

B-hTFR1/hIL1B mice

B-hTFR1/hCD20 mice

B-hCD3EDG/hBCMA/hGPRC5D mice

B-hPD-1/hPD-L1/hIL4/hIL4RA mice

B-hCD3E/hCD28/hDLL3 mice

B-hCD3EDG/hCD19 mice

B-hCOL17A1 mice

B-hCFH mice

B-hPRNP mice

B-hSLC4A1 mice

B-HLA-A2.1/hMAGEA3 MC38

B-hCD16A mice plus(CB-17 SCID)

B-NDG Flt3 KO mice

B-hSERPINB13 mice

B-hFPR1 mice

B-hTSPAN2 mice

B-hCDH17 mice

B-hCAXII mice

B-hFGG mice

B-Ttr KO mice

B-Cfb KO mice

B-Clec7a KO mice(C)

B-I-A/I-E KO mice(C)

B-Mfap5 KO mice

B-Slc29a2 KO mice

B-Ms4a6d KO mice

B-Abcb4 KO mice(C)

B-hTSPAN8 mice

B-hLPA/hAPOC3 mice

B-hCD19/hCD38 mice

B-hCD19/hBCMA mice

B-hCD3EDG/hTFR1 mice

B-hCD3EDG/hEGFR mice

B-hCD16A plus/hEGFR mice

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B-hTGFBR2/hPDGFRA mice

B-hAGT/hPCSK9 plus mice

B-hAPOC3/hPCSK9 plus mice

B-hAGT/hANGPTL3 plus mice

B-hAGT/hAPOC3 mice

B-hANGPTL3 plus/hAPOC3 mice

B-hIL4/hIL4RA/hIL13/hIL13RA1/hOX40/hOX40L mice

B-hLPA plus /hPCSK9 plus mice

B-hLPA/hPCSK9 plus mice

B-hCD3E/hKLK2/hKLK3 mice

B-hCD3E/hCD16A plus mice

B-hCD3E/hCD28/hGPC3 mice

B-Tg(hSIGLEC7/hSIGLEC9), Siglec-E KO mice

B-hITGA7 mice

B-hHER2 MC38 plus

B-Uox KO mice plus

B-hTM4SF1 mice

B-hAGT mice

B-hTNFRSF11A mice

B-hLTBP1(L) mice

B-hCD19-luc-GFP A20

B-hLPAR5 mice

B-hSEZ6 mice

B-hEDNRB mice

B-hLRRC52 mice

B-hCORO1A mice

B-hMCEMP1 mice

B-Lyz2 EGFP-DTR-luciferase mice

B-hHSD17B13 mice

B-hRAGE mice plus

B-HLA-A2.1/hNY-ESO-1 MC38

B-hB2M/HLA-E mice

B-hB4GALT1 mice

B-hGP6 mice

B-hCCL8 mice

B-hWNT16 mice

B-NDG hFLT3LG, Flt3 KO mice

B-hMFAP5 mice

B-hECSCR mice

B-hGPR84 mice

B-hIL17RA/hIL17RB/hIL25 mice

B-hEGFR/hHER3 mice

B-NDG hIL2 mice

B-hGIPR mice

B-hTGFA mice

B-hCRBN mice

B-hAPOA1 mice

B-Rag2 KO mice(C)

B-hXDH plus, Uox KO mice

B-Fmr1 KO mice

B-hLGALS3 mice

B-hPD-1 plus/hPD-L1/hPD-L2 mice

B-hTFF1 mice

B-hPDGFD mice

B-hANPEP mice

B-Muc1 KO rats

B-FcRn KO rats

B-h4-1BB, Tg(hLILRB1/hLILRB4) mice

B-hIL22/hIL22RA1/hIL10RB mice

B-hCD3EDG/hCD19/hBCMA mice

B-hLTA/hTNFA/hLTB/hTNFR2/hTNFR1/hLTBR mice

B-hCFB/hC5 mice

B-hXDH plus, Uox KO mice

B-Cd19-EGFP-DTR-luciferase mice

B-hADAM8 mice

B-Mc4r KO mice

B-hCD46 mice

B-Cd11b-EGFP-DTR-Luc mice

B-hTEK/hTIE1 mice

huHSC-B-NDG hCSF1/hTHPO mice

huPBMC-B-NDG B2m KO mice plus

B-Rag2/F8 DKO mice

B-PrP-hAPP-hPS1 rats

B-Trp53 mKI(p.Arg172His) mice

B-hPD-1/h4-1BB/h4-1BBL mice

B-Rag2/Il2rg DKO mice

B-hIGHA1/hCD89 mice

B-Tg(hMICA) MC38

B-hCRP mice

B-hPROK2 mice

B-hZG16B mice

B-hCLEC1A mice

B-hLPA mice plus

B-Cd8a-EGFP-DTR-luciferase mice

B-Xcr1-EGFP-DTR-luciferase mice

B-Ncr1-EGFP-DTR-luciferase mice

B-hPODXL mice

B-hCD3EDG/hGPC3 mice

B-hCD3E/hCD79B mice

B-hCD28/hPSMA mice

B-Cd11c-EGFP-DTR-Luc mice

B-hIL12RB1/hIL12RB2 mice ad

B-Tg(hCD70-EGFP) MC38

B-hMICB mice

B-hEPOR mice

B-hCMKLR1 mice

B-hRSPO3/hLGR5 mice

B-hEGF mice

B-hPIP mice

B-hPAC1R mice

B-NDG hB2M/HLA-A11.1 mice plus

B-NDG Tg(RORγt-Il2rg) mice

B-hXCR1 mice

B-Tg(Luc-EGFP) U-87 MG

B-hSERPINE2 mice

B-hMMP7 mice

B-hCRTAM mice

B-hFXI mice

B-hTNFRSF11B mice

B-Hbb-bt KO, Hbb-bs KO mice

B-hCD28/hGPC3 mice

B-hCD28/hMSLN mice

B-hEGFR/hMET/hHGF mice

B-hNKP46/hEGFR mice

B-hCD16A/hEGFR mice

B-h4-1BB/hEGFR mice

B-Il36a/Il36b/Il36g KO mice

B-hCD3EDG/hCD19/hCD20 mice

B-hGPR87 mice

B-hBCMA MC38

B-hIL26 mice

B-hTRBC1/hTRBC2 mice

B-hLOX1 mice

B-hSERPINF2 mice

B-Thy1.1 mice

B-hIL4/hIL4RA/hIL13/hIL13RA1 mice

B-hCD3E mice(C)

B-hF3 mice

B-hCLDN3/hCLDN4 mice

B-hBCMA/hGPRC5D MC38

B-hCD8 mice

B-hSORT1 mice plus

B-hGCG mice

B-hTAU mice

B-hAPLP2 mice

B-hCLDN1 mice

B-hADGRG2 mice

B-CD150-iCreERT2 mice

B-hAPOE3 mice

B-hBAMBI mice

B-hILT7 mice

B-HLA-A3.1 mice

B-hNTRK1/hNGF mice

B-hFGB mice

B-hSSTR2 mice

B-hMICA mice

B-hNKP46 mice(CB-17 SCID)

B-hPCSK9 mice plus

B-hPTK7 mice

B-hTREM1/hPGLYRP1 mice

B-hFAP/hIFNGR1/hIFNG/hIFNGR2 mice

B-hTGFBR2/hFAP mice

B-hCD3E/hCD19/hCD20 mice

B-Il20ra KO mice

B-S1pr4 KO mice

B-Apoa1 KO mice

B-Pvrig KO mice(C)

B-Cd22 KO mice(C)

B-Gpr65 KO mice(C)

B-Snca KO mice

B-Uts2r KO mice

B-Cd7 KO mice

B-Cd300lf KO mice

B-hMADCAM1 mice

B-hDPP3 mice

B-hPD-1/hTNFA mice

B-hPD-1/hLAIR1 mice

B-hDR4 mice

B-hADORA2B mice

B-hTEM7R mice

B-hPTH mice

B-hCD32A mice

B-hSLPI mice

B-hFXII mice

B-hLUCA2 mice

B-NDG Kit W41 mice

RenBiologics Assets

B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice

B-hTNFR2/hOX40 mice

B-hIL8 MC38

B-hCDH1 mice

B-hAPOE2 mice

B-hTNC mice

B-hGFRA3 mice

B-hITGA1 mice

B-hTL1A/hα4β7 mice

B-hADAMTS5 mice

B-hIL6ST mice

B-hFLT3LG mice

B-hBPIFA1 mice

B-hCLEC10A mice

B-hITGA2 mice

B-hINHBE mice

B-Tmem176b KO mice

B-Egf KO mice

B-F12 KO mice

B-Pdgfd KO mice

B-Irs2 KO mice

B-Ins2*C96Y mice

B-hIL21R/hIL2RG mice

B-h4-1BB/hFAP mice

B-Mecp2 KO mice

B-hLPA mice

B-hKAAG1 mice

B-hGPR55 mice

B-hADRB1 mice

B-hCXCL3 mice

B-hCD5L mice

B-Tie2-iCreERT2-EGFP mice

B-Rank-iCre mice

B-Lyz2-iCre-EGFP mice

B-Foxc2-iCreERT2 mice

B-Drd1-Cre rats

B-Dmp1-iCre mice

B-Col10a1-iCre mice

B-hTNFR2/hNKG2D mice

B-hVEGFA/hANG2 mice

公示

B-hSEMA7A mice

B-hCD300A mice

B-hKLK2/hKLK3 mice

B-hTSLP/hTSLPR mice(C)

B-hSLC43A2 mice

B-hVPAC1 mice

B-hITGAL mice

B-hSHH mice

B-hLYPD3 mice

B-hSLC16A3 mice

B-hAREG mice

B-hJAG2 mice

B-hVLDLR mice

B-F11r KO mice

B-Fcgr4 KO mice(CB-17 SCID)

B-hCETP mice

B-NDG hB2M/HLA-A24.2 mice plus

B-NDG hB2M/HLA-A3.1 mice plus

B-NDG hALB/hFcRn mice

B-hIL12A/hIL12B/hIL12RB1/hIL12RB2/hPLAUR mice

B-hPD-1/hPD-L1/HLA-A2.1 mice

B-hCD3E/h4-1BB mice(C)

B-hIL4/hIL4RA/hTSLP/hTSLPR plus mice

B-Alb-iCreERT2 mice

B-hLRP10 mice

B-hKLRG1 mice

B-NDG Ces1c KO mice

B-Ces1c KO mice(CB-17 SCID)

B-Ces1c KO mice

B-Bcrp KO mice

B-hCXCL7 mice

B-hPGLYRP1 mice

B-hTCIRG1 mice

B-hMC4R mice

B-hCD151 mice

B-Mcpt5-iCre mice

B-hADAM17 mice

B-hCLEC5A mice(C)

CMC

B-hCD3E/hCD28/hMUC1 mice

B-hCD3E/hCD28/hCD19 mice

B-Tg(WT1 peptide-HLA-A2.1) MC38

B-hRNASE4 mice

B-hF2RL1 mice

B-hAOC3 mice

B-p53 KO mice(C3H)

B-p53 KO mice(FVB)

B-p53 KO mice(A/J)

B-p53 KO mice(ICR)

B-p53 KO mice(C)

B-p53 KO mice(DBA2)

B-Psen1 cKO rats

动物细胞模型及临床前服务

BioMice 小鼠列表

B-Psen2 cKO rats

B-Ox40 KO mice

B-Il5/Il4ra KO mice(C)

B-hIL10RA/hIL2RG mice

B-hPD-1/hPD-L1/hB7-H3 mice

B-hCSPG4 mice

B-hCDH17 B16-F10

B-hTTR*V30M mice

B-hFGFRL1 mice

B-hGDF8 mice

B-hRETN mice

B-hNTRK2 mice

B-vk*MYC mice

B-hCD16A/hNKP46 mice(CB-17 SCID)

B-hCD40/hCD32B mice

B-hFcRn/hCD32B mice

B-hIL4/hIL4RA/hTSLP/hTSLPR mice

B-hIL33/hTSLP/hTSLPR mice plus

B-hIL17RA/hIL17RB mice

B-hCD3E/hDLL3 mice

B-hCD3EDG/HLA-A11.1 mice

B-hCD3EDG/HLA-A24.2 mice

B-hIL2/hIL2RA/hIL2RB/hCCR8 mice

B-hPD-1 plus/hPD-L1/hEGFR mice

B-hPD-1 plus/hPD-L1/hTROP2 mice

B-hPD-1/hPD-L1/hHER2 mice

B-hPD-1 Plus/hGARP mice

B-hPD-1/hPD-L1/hGARP/hTGFB1 mice

B-hTNFR2/hGITR mice

B-hCD209 mice

B-hCXCL7/hCXCL4 mice

B-hMDR1 mice

B-hGPR20 mice

B-Tg(hIFNG/hIL26) mice

B-Fcgr1/Fcgrs KO mice

B-hCD68 mice

B-hIL17B mice

B-hVEGFA MC38 (service only)

B-CAG-Tdtomato cKI rats

B-hLRP6 mice

B-hBDKRB2 mice

B-hFZD7 mice

B-hSUCNR1 mice

B-Upar-EGFP mice

B-hFZD5 mice

B-hFSTL3 mice

B-Mdr1 KO mice

B-hIFNAR1/hIFNAR2 mice

B-hCFP mice

B-hCLDN2 mice

B-hITGA9 mice

B-hLSR mice

B-hHBEGF mice

B-hCTLA4 mice(C)

B-hLRP5 mice

huHSC-B-NDG hIL6 mice

huHSC-B-NDG hTHPO mice

huHSC-B-NDG MGMT3 mice

huHSC-B-NDG HLA-A2.1 mice

B-hANGPTL4 mice plus

CorestemChemon-Biocytogen Joint Symposium Sep. 12th 2023

PDX模型，模拟真实肿瘤生长

B-CAG-Upar-tdTomato cKI mice

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B-hEGFR/hMET mice

B-h4-1BB mice(C)

B-hIL31/hIL31RA/hOSMR/hIL4/hIL4RA mice

B-hCD3E/hEGFR mice

B-hCD3E/hCD16A mice

B-hTROP2/hEGFR mice

B-hTNFR2/hIL2RA mice

B-hCSF1/hCSF1R/hCD40 mice

B-hGFRA1 mice

B-hAPOE4 mice

B-hMUC17 MC38

B-hEREG mice

B-hIL2/hIL2RA/hIL2RB/hIL2RG mice

B-hADAM15 mice

B-hADM mice

B-hFSHB mice

B-hNKG2D mice plus

B-NDG hB2M/HLA-A11.1 mice

B-hICOSL mice

B-hHAMP mice

B-hDLK1 mice

B-hIL13RA1 mice

B-hTIGIT mice(C)

B-hGEP mice

B-hADA mice

B-hTLR4 mice

抗体药物的临床开发

大动物转化医学

小鼠体内药效筛选

抗体发现

RenNano

RenMab

B-hGPR40 mice

B-Pdx-iCre mice

B-hSLAMF7 mice

B-hMST1R mice

B-hEGFL7 mice

B-h4-1BB/hTIGIT mice

B-hTPBG CT26.WT

B-Tg(hEGFR) MC38

B-hMRC1 mice

B-hAPOC3 mice

B-hFSHR mice

B-hANTXR2 mice

B-hCX3CL1 mice

B-hROR1 CT26.WT

B-hADAM9 mice

B-hGPR75 mice

B-hPTHrP mice

B-hF11R mice

B-hNGAL mice

B-hITGB3 mice

B-hTLT2 mice

B-hEPO mice

B-hCCL5 mice

B-hCCR8 mice(C)

B-hAMIGO2 mice

B-hTLT1 mice

B-hCD94/hNKG2A/hNKG2C mice

B-hNCR2 mice

B-hCD16B mice

B-hCFB mice

B-hMMP9 mice

B-hTNFR2 mice(C)

B-hS100A9/hS100A8 mice

B-hMELTF mice

B-hORAI1 mice

B-hXDH mice plus

2022年12月

B-hCDCP1 mice

B-NDG hB2M/HLA-A24.2 mice

B-NDG hB2M/HLA-A3.1 mice

B-hPOSTN mice

B-NDG H2-K1/H2-D1 KO mice

B-hPLXNB2 mice

B-nude rats

Biocytogen San Francisco Office

2023年5月

B-HLA-A24.2 mice

B-hHMMR mice

B-hα4β7 mice

B-hCXCL10 mice

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B-hANXA2 MC38

B-hHRH3 MC38

B-hIL17RA/hIL17RC mice

B-hCDH3 mice

B-hCSPG5 mice

B-hMFGE8 mice

B-hEPHB3 mice

B-hTYRO3 mice

B-hPD-L1/hCD39 MC38

B-hCXCL16 mice

B-hCCL4 mice

B-HLA-A11.1 mice

B-hPD-L1 plus/hCLDN18.2 MC38

B-hGHRL mice

B-hIL20 mice

B-hGPC3 CT26.WT

B-hFOLR1 MC38

B-hIBSP mice

B-hSIGLEC15 CT26.WT

B-hP2RX3 mice

B-hMDK mice

B-hS1PR1 mice

B-hPD-L1 CT26.WT

B-NDG hALB mice

B-hADIPOQ mice

B-hCCL24 mice

B-hLGR4 mice

B-hJAG1 mice

B-hRSPO3 mice

B-hTLR3 mice

B-hCD48 mice

B-hCD19 mice

B-hCTSG mice

B-hCD105 mice

B-hCD30 mice

B-hNOTCH1 mice

B-hIL2RA/hCCR8 mice

B-hIL4/hIL4RA mice(C.B6)

B-hIL10RA/hIL10RB mice

B-hPD-1/hPD-L1/hVEGFR2 mice

B-hPD-1/hTIGIT/hVEGFR2 mice

B-hCD3EDG/hCD70 mice

B-hCD3E/hCD20/hCD38 mice

B-hICOS mice

B-hPD-L1 plus/hTPBG MC38

B-hIL34 MC38

B-hAREG MC38

B-hEBI3 mice

B-hFOLR4 mice

B-hAFP mice

B-hLY6E mice

B-hCD160 mice

B-hCCL11 mice

B-hBCMA CT26.WT

B-CD45.1 mice

B-hMUC17 mice

B-hTL1A mice

B-hCD16A/hNKG2D mice

B-hB7-H3/hNKP46 mice

B-hB7-H3/hNKG2D mice

B-hCD16A/hNKP46 mice

B-hTNFR2/hCCR8 mice

B-hPD-1 plus/hTGFBR2 mice

B-hPD-1/hPD-L1/hCD73 mice

B-hPD-1 plus/hPD-L1 mice

B-hCD3EDG/HLA-A2.1 mice

B-hIL31/hIL31RA/hOSM/hOSMR mice

B-NDG hIL15, FcγR KO mice

B-Gpr75 KO mice

B-Il18bp KO mice

B-Ncr1 KO mice(CB-17 SCID)

B-Retn KO mice

B-Rag2/F8 DKO mice

B-hRTN4R mice

huHSC-B-NDG hIL15 mice

huNK-B-NDG hIL15 mice

B-hCLU mice

B-hCD226/hTIGIT mice

B-hENPP3 MC38

B-hTIMP1 mice

B-hBST2 mice

B-hICAM1 mice

B-hCD23 mice

B-hLGALS3BP mice

B-hHCAR1 mice

B-hEVA-1 mice

B-hIGF2R mice

B-hSEMA4D mice

B-NDG hB2M/HLA-A2.1 mice plus

B-hMUC1 mice

B-hIL31/hIL31RA/hOSMR mice

B-hIL9 mice

B-hC3 mice

B-hOSM/hOSMR mice

B-hTSLP/hTSLPR mice plus

B-hIL18BP mice

B-hTIGIT mice(C)

B-hIL17RB/hIL25 mice

B-hDLL4 mice

B-hDLL3 mice

BDL高级经理/副总监/总监

B-hOLFML3 MC38

B-hMET MC38

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B-hITGB8 mice

B-hLGALS9 mice

B-hTIM4/hTIM1 mice

B-hDLL1 mice

B-hVEGFR1 mice

B-hWNT3A mice

B-Foxp3-EGFP-DTR-Luc mice

B-hIGF1R mice

huHSC-B-NDG mice

huPBMC-B-NDG mice

B-NDG hGM-CSF mice

B-NDG hairless mice

B-NDG hIL7 mice

B-NDG H2-Ab1 KO mice

B-PrP-hAPP-hPS1 rats

B-Trp53 mKI(p.Arg172His) mice

B-Adipor1 KO mice

B-Grn KO mice

B-hKIT/hKITLG mice

B-hIL13/hOX40 mice

B-hICAM3 mice

B-hCD200/hCD200R mice

B-hIL10/hIL10RA/hIL10RB mice

B-hIL22RA1/hIL10RB mice

B-hIL22/hIL22RA1 mice

B-hCD3EDG/hCD28/hTROP2 mice

B-hCD3EDG/hCD28/hCD20 mice

B-hIL13/hOX40/hOX40L mice

B-hPD-1 plus/hPD-L1/hCD80 mice

B-hPD-1/hPD-L1/hVEGFA mice

B-hCD3EDG/h4-1BB mice

B-hCD3E/hROR1 mice

B-hCD3E/hCD30 mice

B-hPD-L1/hPVRIG mice

B-Ifnar1 KO mice

B-hIFNAR2 mice

B-hLIF mice

B-hCRTH2 mice plus

B-hCD3E/h4-1BB/HLA-A2.1 mice

B-hFGF21 mice

B-hGPC1 mice

STAM-NASH模型

B-hLRRC15 MC38

B-hEFEMP1 MC38

B-Tg(mEfna3) MC38

B-hMMP-8 MC38

B-hCD59 mice

B-hANGPTL3 mice plus

B-Luc THP-1

CT26.WT-OVA

B-Tg(Luc) A549

B-Fbxl5 KO mice

B-Fbxl3 KO mice

B-Fam13c KO mice

B-Eya2 KO mice

B-Esrrg KO mice

B-Elovl7 KO mice

B-Elovl6 KO mice

B-Elovl5 KO mice

B-Elavl2 KO mice

B-Elane KO mice

B-Luc-EGFP SU-DHL-1

B-Eepd1 KO mice

B-Eed KO mice

B-E2f1 KO mice

B-Dubr KO mice

B-Dppa3 KO mice

B-Dnajb6 KO mice

B-Dmrta1 KO mice

B-Disc1 KO mice

B-Dhx9 KO mice

B-Dcbld1 KO mice

B-Daxx KO mice

B-Dag1 KO mice

B-Cyp7a1 KO mice

B-Cyfip2 KO mice

B-Cul5 KO mice

B-Ctsl KO mice

B-Ctsk KO mice

B-Ctbp1 KO mice

B-Cstf2 KO mice

B-Luc CT26.WT

B-Csf2rb KO mice

B-Crispld2 KO mice

B-Crbn KO mice

B-Cpt1a KO mice

B-Cox20 KO mice

B-Cltc KO mice

B-Cln6 KO mice

B-Clec1b KO mice

B-Chfr KO mice

B-Chd4 KO mice

B-Chd3 KO mice

B-Chd1l KO mice

B-Chat KO mice

B-Cfl1 KO mice

B-Cers4 KO mice

B-Cep89 KO mice

B-Celsr3 KO mice

B-Cebpb KO mice

B-Cdkn2a KO mice

B-Cdkl5 KO mice

B-Cd79a KO mice

B-Tg(Luc) HCT 116

B-Cd2ap KO mice

B-Ccr10 KO mice

B-Cckar KO mice

B-Ccer1 KO mice

B-Cavin3 KO mice

B-Castor2 KO mice

B-Casp4 KO mice

B-Casp1 KO mice

B-Car2 KO mice

B-Capn1 KO mice

B-Camsap2 KO mice

B-Camsap1 KO mice

B-Camkk2 KO mice

B-Calcb KO mice

B-Cacna1c KO mice

B-Brn3b KO mice

B-Becn1 KO mice

B-Bdp1 KO mice

B-Bcdin3d KO mice

B-Tg(Luc) RKO

B-Fat2 KO mice

B-Eya1 KO mice

B-Etv4 KO mice

B-Dek KO mice

B-Cldn7 KO mice

B-Cdca2 KO mice

B-Cars KO mice

B-Fam46a KO mice

B-Ell2 KO mice

B-Eif2ak1 KO mice

B-Dpyd KO mice

B-Crispld1 KO mice

B-Cntn6 KO mice

B-Brd9 KO mice

B-Camsap3 KO mice

B-Bap1 KO mice

B-Tnfaip3 KO mice

B-Tmigd1 KO mice

B-Tmem215 KO mice

B-Tmem182 KO mice

B-Tmem141 KO mice

B-Tmem119 KO mice

B-Tmc1 KO mice

B-Tns1 KO mice

B-Tox3 KO mice

B-Trerf1 KO mice

B-Trhr KO mice

B-Trim27 KO mice

B-Trim28 KO mice

B-Trip12 KO mice

B-Trp63 KO mice

B-Trpv2 KO mice

B-Twist1 KO mice

B-Ubap1 KO mice

B-Ube2cbp KO mice

B-Ube2s KO mice

B-Ube3b KO mice

B-Ube4b KO mice

B-Ubxn4 KO mice

B-Uchl5 KO mice

B-Uhrf1 KO mice

B-Vkorc1l1 KO mice

B-Vmn1r69 KO mice

B-Vsnl1 KO mice

B-Wdfy1 KO mice

B-Wdr33 KO mice

B-Whsc1 KO mice

B-Wwc1 KO mice

B-Yjefn3 KO mice

B-Ythdf2 KO mice

B-Ywhaz KO mice

B-Zbed6 KO mice

B-Zbtb11 KO mice

B-Zbtb16 KO mice

B-Zdhhc20 KO mice

B-Zfp318 KO mice

B-Zfp598 KO mice

B-Zfp683 KO mice

B-Zfp697 KO mice

B-Znhit3 KO mice

B-Chl1 KO mice

B-Ptprd KO mice

B-Ecsit KO mice

B-Tkfc KO mice

B-Thra KO mice

B-Tff3 KO mice

B-Tfe3 KO mice

B-Tert KO mice

B-Tcf7 KO mice

B-Tcf21 KO mice

B-Tbx2 KO mice

B-Tbc1d5 KO mice

B-Tbc1d24 KO mice

B-Taok2 KO mice

B-Syce1 KO mice

B-Suv39h1 KO mice

B-Sumo1 KO mice

B-Sult2b1 KO mice

B-Sugp2 KO mice

B-Sucnr1 KO mice

B-Stk38 KO mice

B-Stk25 KO mice

B-Sting KO mice

B-Stat1 KO mice

B-Stap2 KO mice

B-Stac2 KO mice

B-Ss18l1 KO mice

B-Srr KO mice

B-Fgf23 KO mice

B-Madcam1 KO mice

B-Muc3 KO mice

B-Fgfrl1 KO mice

B-Trem2 KO mice(C)

B-Tlr3 KO mice

B-Clec9a ko mice

B-Klk1 KO mice

B-Tlr4 KO mice

B-Vsir KO mice

B-Cd69 KO mice

B-Cd63 KO mice

B-Cd6 KO mice

B-Cd52 KO mice

B-Cd5 KO mice

B-Cd47 KO mice(C)

B-Cd47 KO mice

B-Cd43 KO mice

B-Cd40 KO mice

B-Cd34 KO mice

B-Cd28 KO mice

B-Cd276 KO mice(C)

B-Cd274 KO mice

B-Cd248 KO mice

B-Cd24 KO mice

B-Cd23 KO mice

B-Cd200r1 KO mice

B-Cd2 KO mice

B-Cd180 KO mice

B-Fcgr4 KO mice

B-Cd160 KO mice

B-Cd138 KO mice

B-Ccr9 KO mice

B-Ccr8 KO mice

B-Ccr7 KO mice

B-Ccr6 KO mice

B-Ccr5 KO mice(C)

B-Ccr5 KO mice

B-Ccr4 KO mice(C)

B-Ccr3 KO mice

B-Ccr2 KO mice(C)

B-Ccr2 KO mice

B-Ccr1 KO mice

B-Ccn2 KO mice

B-Ccn1 KO mice

B-Ccl5 KO mice

B-Ccl4 KO mice

B-Ccl3 KO mice

B-Ccl20 KO mice

B-CB1 KO mice

B-Car9 KO mice

B-Calca KO mice

B-C5ar2 KO mice

B-C5ar1 KO mice(C)

B-C5a KO mice

B-Btla KO mice

B-Bst2 KO mice

B-Brca1 KO mice

B-Brca KO mice

B-B7-h4 KO mice(C)

B-Axl KO mice

B-Asic1 KO mice

B-Artn KO mice

B-Areg KO mice

B-App KO mice

B-Aplnr KO mice

B-Aoc3 KO mice

B-Angptl8 KO mice

B-Angptl3 KO mice

B-Angpt1 KO mice

B-Amigo2 KO mice

B-Amhr2 KO mice

B-Adm KO mice

B-Adam15 KO mice

B-A2aR KO mice(C)

B-Trem2 KO mice

B-Spp1 KO mice

B-Sirpa KO mice

B-Ptprs KO mice

B-Nt5e KO mice

B-Lag3 KO mice

B-Icos KO mice

B-Hk2 KO mice

B-Gsdmd KO mice

B-Gjb2 KO mice

B-Fcer1a KO mice

B-Ephb4 KO mice

B-Cxcl4 KO mice

B-Crth2 KO mice

B-Cnr2 KO mice

B-Cd38 KO mice

B-Ccl2 KO mice

B-C5ar1 KO mice

B-Adipoq KO mice

B-Khsrp KO mice

B-Kdm3a KO mice

B-Kctd17 KO mice

B-Kcnk6 KO mice

B-Jmjd6 KO mice

B-Jak2 KO mice

B-Itk KO mice

B-Irf7 KO mice

B-Irf2bp2 KO mice

B-Il36a KO mice

B-Ikbip KO mice

B-Igha KO mice

B-Igfbp4 KO mice

B-Igf2bp2 KO mice

B-Igf2bp1 KO mice

B-Ifitm3 KO mice

B-Ifi30 KO mice

B-Ifi27 KO mice

B-Id2 KO mice

B-Hspb1 KO mice

B-Hsd17b6 KO mice

B-Hs3st5 KO mice

B-Hs3st4 KO mice

B-Hs3st1 KO mice

B-Homer2 KO mice

B-Hoga1 KO mice

B-Hnrnpf KO mice

B-Hk3 KO mice

B-Hilpda KO mice(C)

B-Hectd3 KO mice

B-Hddc3 KO mice

B-Hcn2 KO mice

B-Gys1 KO mice

B-Gusb KO mice

B-Gtf2i KO mice

B-Gsdme KO mice

B-Gsdmc KO mice

B-Gsdma KO mice

B-Grin2a KO mice

B-Gprc6a KO mice

B-Gpr88 KO mice

B-Gpr4 KO mice

B-Gpr35 KO mice

B-Gpr183 KO mice

B-Gpr174 KO mice

B-Gpd1 KO mice

B-Gpbar1 KO mice

B-Gpatch1 KO mice

B-Gm15222 KO mice

B-Gltp KO mice

B-Glrx KO mice

B-Gigyf1 KO mice

B-Gch1 KO mice

B-Gc KO mice

B-Gata2 KO mice

B-Gas2 KO mice

B-Vipr1 KO mice

B-Gamt KO mice

B-Vcp KO mice

B-G6pc KO mice

B-G181 KO mice

B-Fus KO mice

B-Ftcd KO mice

B-Fscn1 KO mice

B-Frzb KO mice

B-Fpr1 KO mice

B-Foxp3 KO mice

B-Foxm1 KO mice

B-Foxg1 KO mice

B-Foxf1 KO mice

B-Foxa3 KO mice

B-Flot2 KO mice

B-Fitm2 KO mice

B-Fitm1 KO mice

B-Tnfsf14 KO mice

B-Ficd KO mice

B-Tnfsf11 KO mice

B-Fibin KO mice

B-Tnfsf10 KO mice

B-Fgd5 KO mice

B-Tnfrsf18 KO mice

B-Fez1 KO mice

B-Fcgr3 KO mice

B-Tnfrsf17 KO mice

B-Fbxw2 KO mice

B-Tlr2 KO mice

B-Tl1a KO mice

B-Fbxo45 KO mice

B-Fbxo32 KO mice

B-Tim3 KO mice

B-Fbxo28 KO mice

B-Tigit KO mice

B-Tgm2 KO mice

B-Tgfb2 KO mice

B-Tff1 KO mice

B-Steap1 KO mice

B-Sstr2 KO mice

B-Fbxo25 KO mice

B-Sost KO mice(C)

B-Slc16a1 KO mice

B-Siglecg KO mice

B-Siglec15 KO mice

B-Serpine1 KO mice

B-Serpinb13 KO mice

B-Selplg KO mice

B-S100a9 KO mice

B-Rtn4r KO mice

B-Rspo1 KO mice

B-Robo4 KO mice

B-Robo1 KO mice

B-Rhob KO mice

B-Pvrig KO mice

B-Pvr KO mice

B-Psma KO mice

B-Psca KO mice

B-Postn KO mice

B-Pld4 mice

B-Plau KO mice

B-Pdgfrb KO mice

B-PD-1 KO mice

B-P2rx7 KO mice

B-Olr1 KO mice

B-Cd73 KO mice(C)

B-Nrros KO mice

B-NKp46 KO mice

B-Nkg2d KO mice

B-Nkg2a KO mice

B-Ngf KO mice

B-Nectin4 KO mice

B-Nampt KO mice

B-Muc1 KO mice

B-Msln KO mice

B-Mif KO mice

B-Marco KO mice

B-Mapt KO mice

B-Mag KO mice

B-Maea KO mice

B-Lypd3 KO mice

B-Lrrc32 KO mice

B-Lrrc15 KO mice

B-Lrp10 KO mice

B-Lair1 KO mice

B-Kras KO mice

B-Itgb3 KO mice

B-Itgam KO mice

B-Itga11 KO mice

B-Il6ra KO mice(C)

B-Il6 KO mice(C)

B-Il5ra KO mice

B-Il5ra KO mice(C)

B-Il5 KO mice(C)

B-Il4ra KO mice(C)

B-Il4/Il5ra KO mice(C)

B-Il4 KO mice(C)

B-Il3ra KO mice(C)

B-Il34 KO mice

B-Il33 KO mice(C)

B-Il33 KO mice

B-Il31ra KO mice(C)

B-Il31 KO mice(C)

B-Il3 KO mice(C)

B-Baiap2 KO mice

B-Il2rg KO mice

B-B4galt7 KO mice

B-Avpr1a KO mice

B-Atp6v1a KO mice

B-Il27 KO mice(C)

B-Atp6v0c KO mice

B-Atg5 KO mice

B-Atg16l1 KO mice

B-Atf6b KO mice

B-Atf4 KO mice

B-Atat1 KO mice(FVB)

B-Atat1 KO mice

B-Il23r KO mice(C)

B-Ash1l KO mice

B-Asah2 KO mice

B-Arr3 KO mice

B-Armc5 KO mice

B-Arl13b KO mice

B-Arid3a KO mice

B-Arid1b KO mice

B-Arhgap39 KO mice

B-Arg2 KO mice

B-Apela KO mice

B-Apc KO mice

B-Ano10 KO mice

B-Ankib1 KO mice

B-Alkbh5 KO mice

B-Aldh7a1 KO mice

B-Aldh2 KO mice

B-AK050834 KO mice

B-Aim2 KO mice

B-AI662270 KO mice

B-AI593442 KO mice

B-Ahr KO mice

B-Agbl5 KO mice

B-Aff4 KO mice

B-Adrb2 KO mice

B-Adnp KO mice

B-Adipor2 KO mice

B-Adgrg3 KO mice

B-Actg1 KO mice

B-Actb KO mice

B-Acss2 KO mice

B-Acss1 KO mice

B-Acsl4 KO mice

B-Acp5 KO mice

B-Ackr2 KO mice

B-Acadm KO mice

B-Abhd17b KO mice

B-2610301B20RikR179W KO mice

B-Osm KO mice

B-Ybx1 KO mice

B-Vdr KO mice

B-Ubr2 KO mice

B-Tfeb KO mice

B-Taar1 KO mice

B-Surf4 KO mice

B-Stk24 KO mice

B-Sox10 KO mice

B-Shmt2 KO mice

B-Shank2 KO mice

B-Sars KO mice

B-S1pr2 KO mice

B-Rora KO mice

B-Prkaa1 KO mice

B-Pparg KO mice

B-Osr2 KO mice

B-MRGPRE KO mice

B-Mgea5 KO mice

B-Mdga2 KO mice

B-Mb21d1 KO mice

B-Map4k3 KO mice

B-Ltn1 KO mice

B-Lhcgr KO mice

B-Iqsec3 KO mice

B-Hnrnpa2b1 KO mice

B-Hmox1 KO mice

B-H19 KO mice

B-Gzma KO mice

B-Grin2b KO mice

B-Gm15915 KO mice

B-Duox2 KO mice

B-Dnase1l3 KO mice

B-Cyp24a1 KO mice

B-Azin1 KO mice

B-Alpk1 KO mice

B-Il23a KO mice(C)

B-Il21r KO mice

B-Il21 KO mice(C)

B-Il20 KO mice

B-Il1rl1 KO mice

B-Il1b KO mice(C)

B-Il1a KO mice(C)

B-Il19 KO mice

B-Il18 KO mice

B-Il17rc KO mice(C)

B-Il17ra KO mice(C)

B-Il17f KO mice(C)

B-Il17d KO mice(C)

B-Il17c KO mice

B-Il17b KO mice(C)

B-Il17a KO mice(C)

B-Il13 KO mice(C)

B-Il11 KO mice(C)

B-Il10 KO mice(C)

B-Il10 KO mice

B-IgE KO mice

B-Ifnb1 KO mice

B-Icosl KO mice

B-Ibsp KO mice

B-Hmgb1 KO mice

B-B2m KO mice

B-Hgfac KO mice

B-hFFAR1 KO mice

B-Hbegf KO mice

B-Hamp KO mice

B-Grm7 KO mice

B-Gprc5d KO mice

B-Gpr84 KO mice

B-Gpr55 KO mice

B-Gpc1 KO mice

B-Glp1r KO mice(C)

B-Gjb2 KO mice(FVB)

B-Pfn1 KO mice

B-Peg3 KO mice

B-Pdk1 KO mice

B-Gjb2 KO mice(CBA/CaJ)

B-Pde5a KO mice

B-Ghrl KO mice

B-Pde4b KO mice

B-Ghr KO mice

B-Pde2a KO mice

B-Gdf15 KO mice

B-Pdap1 KO mice

B-Pcna KO mice

B-Gcgr KO mice(C)

B-Pcif1 KO mice

B-Pcdha1 KO mice

B-Gcgr KO mice

B-Paxip1 KO mice

B-Folr4 KO mice

B-P4ha1 KO mice

B-Oxt KO mice

B-Fn14 KO mice

B-Optn KO mice

B-Fgl2 KO mice

B-Olig2 KO mice

B-Fgfr3 KO mice

B-Nxpe2 KO mice

B-Fgf21 KO mice

B-Nsun2 KO mice

B-Nrgn KO mice

B-Nr1i3 KO mice

B-Fcgr2b KO mice

B-Nr1d1 KO mice

B-Fap KO mice

B-Esr1 KO mice

B-Nr0b2 KO mice

B-Npy2r KO mice

B-Epor KO mice

B-Npy1r KO mice

B-Epcam KO mice

B-Nptxr KO mice

B-Entpd1 KO mice

B-Nptx2 KO mice

B-Dpp4 KO mice

B-Nptx1 KO mice

B-Dlk1 KO mice

B-Nosip KO mice

B-Srebf2 KO mice

B-Nmnat1 KO mice

B-Ddr1 KO mice

B-Src KO mice

B-Nme1/Nme2 KO mice

B-CypA KO mice

B-Sqle KO mice

B-Sptlc2 KO mice

B-Nlrc5 KO mice

B-Cxcr6 KO mice

B-Sptlc1 KO mice

B-Nlrc3 KO mice

B-Cxcr5 KO mice

B-Sphk2 KO mice

B-Nfatc2 KO mice

B-Sox3 KO mice

B-Cxcr3 KO mice

B-Ndst2 KO mice

B-Son KO mice

B-Cxcl9 KO mice

B-Socs1 KO mice

B-Ndst1 KO mice

B-Snhg5 KO mice

B-Cxcl16 KO mice

B-Smpd3 KO mice

B-Nat10 KO mice

B-Smo KO mice

B-Cxcl13 KO mice

B-Nalcn KO mice

B-Smarcc1 KO mice

B-Cxcl1 KO mice

B-Smad3 KO mice

B-Slitrk5 KO mice

B-Naa20 KO mice

B-Cx3cr1 KO mice(C)

B-Slc7a4 KO mice

B-Myh9 KO mice

B-Slc6a17 KO mice

B-Cx3cl1 KO mice

B-Myh7 KO mice

B-Cspg5 KO mice

B-Mthfr KO mice

B-Mthfd2 KO mice

B-Csf3 KO mice

B-Csf2ra KO mice(C)

B-Msl2 KO mice

B-Mrs2 KO mice

B-Csf2 KO mice(C)

B-Mrgprg KO mice

B-Csf2 KO mice

B-Mrgprf KO mice

B-Mr1 KO mice

B-Crtam KO mice

B-Mpig6b KO mice

B-Cmtm6 KO mice

B-Clec14a KO mice

B-Cldn6 KO mice

B-Chil1 KO mice

B-Morrbid KO mice

B-Mmrn2 KO mice

B-Cfh KO mice

B-Mmachc KO mice

B-Cfd KO mice

B-Mlk3 KO mice

B-Mir770 KO mice

B-Mir670 KO mice

B-Cdh3 KO mice

B-Mir455 KO mice

B-Cd96 KO mice

B-Mir342 KO mice

B-Slc37a4 KO mice

B-Slc35d3 KO mice

B-Cd93 KO mice

B-Mir335 KO mice

B-Slc30a1 KO mice

B-Mir296 KO mice

B-Cd81 KO mice

B-Slc2a9 KO mice

B-Slc2a3 KO mice

B-Mir204 KO mice

B-Slc23a2 KO mice

B-Mir142 KO mice

B-Slc20a2 KO mice

B-Slc15a2 KO mice

B-Slc10a4 KO mice

B-Mettl4 KO mice

B-Six2 KO mice

B-Cd79b KO mice

B-Mettl14 KO mice

B-Sirt6 KO mice

B-Sirt3 KO mice

B-Sirt1 KO mice

B-Me2 KO mice

B-Sik3 KO mice

B-Sik2 KO mice

B-Mcu KO mice

B-Sik1 KO mice

B-Sigmar1 KO mice

B-Mas1 KO mice

B-Siglece KO mice

B-Setdb1 KO mice

B-Map4k5 KO mice

B-Setd6 KO mice

B-Sesn2 KO mice

B-Map4k4 KO mice

B-Serpinb1a KO mice

B-Serinc5 KO mice

B-Map4k1 KO mice

B-Serinc3 KO mice

B-Map3k3 KO mice

B-Sema4c KO mice

B-Sdhaf4 KO mice

B-Scrt2 KO mice

B-Scnn1a KO mice

B-Scn2a KO mice

B-Scg2 KO mice

B-Scd1m KO mice

B-Satb1 KO mice

B-Sarm1 KO mice

B-Sacm1l KO mice

B-Runx3 KO mice

B-Maf KO mice

B-Runx1 KO mice

B-Rtkn2 KO mice

B-Ly6g6c KO mice

B-Rtf1 KO mice

B-Rpl22 KO mice

B-Rnf214 KO mice

B-Rnf10 KO mice

B-Ripk3 KO mice

B-Ly6a KO mice

B-Ripk1 KO mice

B-Ltk KO mice

B-Lrrtm4 KO mice

B-Rbbp5 KO mice

B-Rab39b KO mice

B-Rab27b KO mice

B-Lrrtm2 KO mice

B-Rab27a KO mice

B-Lrrc8a KO mice

B-Qprt KO mice

B-Pygl KO mice

B-Lrp2 KO mice

B-Pycrl KO mice

B-Pxdn KO mice

B-Pwwp2b KO mice

B-Ptk2 KO mice

B-Ptges KO mice

B-Ptbp1 KO mice

B-Lpcat1 KO mice

B-Prkar2b KO mice

B-Prdx1 KO mice

B-Lhpp KO mice

B-Prag1 KO mice

B-Ppm1d KO mice

B-Lhfpl5 KO mice

B-Plod2 KO mice

B-Lect2 KO mice

B-Plekhg2 KO mice

B-Plekhf1 KO mice

B-Laptm4b KO mice

B-Pim1 KO mice

B-Krt4 KO mice

B-Pik3cgcm KO mice

B-Pik3cd KO mice

B-Phf23 KO mice

B-Kmt5c KO mice

B-Klf9 KO mice

B-Phb KO mice

B-Klf4 KO mice

B-Ccl1 KO mice

B-Zswim4 KO mice

B-Trop2 KO mice

B-Zswim8 KO mice

B-Tnfsf18 KO mice

全人纳米抗体RenNano小鼠

B-hPD-L1 plus/hPCSK9 MC38

B-hNPR1 mice

B-hCAIX mice

B-hFOLR1/hFOLR2 mice

B-hCCR8/hCCL1 mice

B-hPDGFRA mice

B-hTREM2 mice(C)

B-hDDR1 mice

B-hCD32B mice

B-hALCAM mice

B-hGPR35 mice

B-hCB2 mice

B-hITGA6 mice

B-hNKP46 mice(C)

B-hEGFR mice

B-hNCR3 mice

B-hCD3E/HLA-A2.1 mice

B-hIL33/hTSLP/hTSLPR mice

原位肿瘤模型

检测项目

DTH小鼠模型Dexamethasone药效验证

OXA或KIH诱导DTH小鼠疾病模型的建立

迟发性超敏反应（DTH）疾病模型

骨质疏松模型构建及验证

骨质疏松模型

ALT诱导的肺炎小鼠模型

木瓜蛋白酶诱导的肺炎小鼠模型

Pristane诱导的系统性红斑狼疮小鼠模型

博来霉素诱导的肺纤维化小鼠模型

胶原抗体诱导型关节炎（collagen antibody induced arthritis, CAIA）模型的构建

CD4+CD45RB high T 细胞诱导的IBD小鼠模型

TNBS诱导的IBD小鼠模型

ALT诱导的小鼠模型

HDM诱导的急性哮喘模型的构建及验证

草酸饮食诱导的慢性肾病（CKD）模型

ApoE KO 小鼠动脉粥样硬化模型

TAA（硫代乙酰胺）诱导的肝纤维化模型

胆管结扎诱导的肝纤维化

CCL4 诱导的肝纤维化模型

ConA诱导的肝损伤模型

APAP诱导的急性肝损伤小鼠模型

B-hTNFR2/hTNFR1/hLTBR mice

B-hCD133 mice

B-hCD69 mice

B-hHER3 mice

B-hCD79A mice

B-hMSLN MC38

B-hPD-1/hPD-L1/hVSIR mice

B-Cd38-EGFP KI mice

B-Plaur-EGFP mice

B-hHER2/hTROP2 mice

B-hPD-1/hPD-L1, Tg(hLILRB2/hLILRB3) mice

B-hEMP2 mice

B-hCDH17 MC38

B-MUP-uPA mice

B-hCD40/hFcRn mice

B-hNECTIN4 mice

B-hIgE/hFCER1A mice

B-hVWF mice

B-hCD200 MC38

B-hTROP2 CT26.WT

B-hHER2 CT26.WT

B-hPD-L1 plus/hROR1 MC38

B-hIL5/hIL5RA mice

B-hIL5 mice

B-hADAM9 MC38

B-hCXCL13/hCXCR5 mice

B-hBDCA2 mice

B-hB7-H3 mice (C)

B-hNTRK3 mice

B-Tg(mCldn2) MC38

B-hITGA7 MC38

B-hCAXII MC38

B-hCD106 MC38

B-NDG MGMT3 mice

B-hCD98HC/Rag2 KO mice

B-hPD-L1/hA2AR mice

B-hPD-1/hPD-L1/hCSF1/hCSF1R mice

B-hIFNGR1/hIFNG/hIFNGR2 mice

B-hPD-1/hPCSK9 mice

B-hIL11/hIL11RA mice

B-hIL36R/hIL1RACP mice

B-hPD-1/hPD-L1/hTIGIT/hPVRIG mice

B-hPD-1/hPD-L1/hCD3E mice

B-hCD3E/hCD28/h4-1BB mice

B-hPD-1 plus/hIL21R mice

B-hFGL1/hLAG3 plus mice

B-hTFR1/hTREM2 mice

B-h4-1BB/hHER2 mice

B-hPD-1/hPD-L1 mice(C)

B-hCD3E/hEPCAM mice

B-hMERTK/hGAS6 mice

B-hc-MPL MC38

B-hCD56 MC38

B-hLRRN1 MC38

B-hCD151 MC38

B-hSTEAP1 MC38

B-hFCER1A mice

B-hROR1 mice

B-hCD24 mice plus

B-hIL2RB/hIL15 mice

B-hUPA/hUPAR mice

B-hCD3E/hMSLN mice

B-hCD3E/hGPRC5D mice

B-hCD3EDG/hBCMA mice

B-hCD3E/hGPC3 mice

B-hCD3E/hCD33 mice

B-hCD3E/hAMHR2 mice

B-hCD3E/hB7-H4 mice

B-hCD3E/hPSMA mice

B-hCD3E/hCD70 mice

B-hCD3E/hCD37 mice

B-hCD3E/hCEACAM1 mice

B-hCD3E/hFAP mice

B-hCD3E/hB7-H3 mice

B-hCD3E/hTPBG mice

B-Tg(hIL8) mice

B-hIGFBP7 mice

B-Tg(mCd70) MC38

B-hGPNMB MC38

B-hALB MC38

B-hCD10 MC38

肥胖和糖尿病模型

B-hGAS6 MC38

B-hMAG mice

B-hJAM3 mice

B-hCD95 mice

B-hCD3E/hHER2 mice

B-Tg(hHER2/hTROP2) MC38

B-hGARP/hTGFB1 mice

B-hBAFF/hBAFFR mice

B-hLAIR1 mice

B-hCTLA4/hCCR8 mice

B-hMARCO mice

B-hANGPTL3 mice

2022年9月

B-hCD112 MC38

B-hCCR9 MC38

B-hIL15/hIL15RA mice

B-h4-1BB/hTNFR2 mice plus

B-hDKK1 mice

B-hCD163 mice

B-hSPN MC38

B-Tg(mMeltf) MC38

B-Tg(mMmp8) MC38

B-Tg(mIgfbp2) MC38

B-Tg(mGpc2) MC38

B-Tg(mSez6l2) MC38

B-hTGFB1 mice

B-hCD1D mice

B-hTFPI mice

B-hIL2RB/hIL2RG/hIL15/hIL15RA mice

B-hANG2 mice

B-hC1Q mice

B-hCCR1 mice

B-hCXCR6 mice

B-hGLP1R/hGCGR mice

B-hPD-L1 plus/hHER2 MC38

B-HLA-E plus/hPD-L1 MC38

B-hEPCAM B16-F10

B-hEPCAM LLC1

B-hCXCL1 mice

B-hCD9 mice

B-hLAT1 mice

B-hUPAR mice

B-hMUC1 MC38

B-hDLL3 B16-F10

B-hTLR8/hTLR7 mice

B-hPD-1/hPD-L1/hCD94/hNKG2A mice

B-hGRP mice

B-hFGL2 mice

B-hTNFA/hTNFR2/hTNFR1 mice

B-hCD155/hCD112 mice

B-hNRP1 mice

B-hCSF3 mice

B-hB2M/HLA-G MC38

B-hPDGFB mice

B-hCD73/h4-1BB mice

B-hCTLA4/hTNFR2 mice

B-hPD-1/hPD-L1,Igh-J KO mice

B-hPD-1 mice(C)

B-hPD-L1 mice(C)

B-hCD16A mice(C)

B-hCD38 mice

B-hGFRAL mice

B-hIL18 mice

B-Tg(mCd30) MC38

B-Tg(mMet) MC38

B-Tg(mItga7) MC38

B-Tg(mAbcb1b) MC38

B-Tg(mAmhr2) MC38

B-Tg(mEgfr) MC38

B-Tg(mChil1) MC38

B-Tg(mAlb) MC38

B-Tg(mIgfbp7) MC38

B-Tg(mCcr9) MC38

B-Tg(mEpha4) MC38

B-Tg(mCdh17) MC38

B-Tg(mHpn) MC38

B-hUPA mice

B-Tg(mLypd3) MC38

B-Tg(mCar12) MC38

B-Tg(mLrrn1) MC38

B-Tg(mEntpd2) MC38

B-Tg(mSez6) MC38

B-Tg(mMpl) MC38

B-hCTLA4/hTIGIT mice

B-hJAM3 MC38

B-hCCL20 mice

B-hCCR3 mice

B-hCD6 mice

B-hCLEC14A mice

B-hHER3 MC38

B-Cd155-EGFP KI mice

B-hPD-1/hPD-L1/hCCR8 mice

2022年3月

B-hUPAR MC38

B-hMIF mice

B-hRGMA mice

老龄鼠

老龄鼠

B-hIL2RB/hIL2RG mice

B-hCTLA4/hIL2RA mice

B-hCXCR3 mice

B-hCCL22 mice

B-hTDGF1 mice

B-hCFD mice

B-hPD-L1/hB7-H3 MC38

B-Tg(hLILRB2/hLILRB3/hLILRB1/hLILRB4) mice

B-hIFNB1 mice

B-hIL19 mice

B-hSELE/hSELL mice

B-hCCL3 mice

B-Tg(mGpa33) MC38

B-Tg(mAreg) MC38

B-hGUCY2C MC38

B-hGPC3 MC38 plus

B-NDG MHC I/II DKO mice plus

B-hEPCAM mice

B-hCCN4 mice

B-hS100A9 mice

B-hNKG2D mice

B-hCGRP mice

B-hB2M/HLA-G mice

B-hVEGFA mice

B-hSIRPA/hCD47/hCD3E/hCD28 mice

B-hFAP mice

AACR 2022: Evaluating Delivery of TFR1-targeting Therapies to the CNS in a Novel Humanized TFR1 Mouse Model

AACR 2022: Developing a Translational Tool for GLP-1-Based Therapeutic Agonists in Humanized GLP1R Mice

AACR 2022: YH008, a PD-1-CD40 Bispecific Antibody, Inhibits Tumor Growth In Vivo Through PD-1-Dependent Activation of CD40 Signaling

AACR 2022: B-hIL12A/hIL12B/hIL12RB1/hIL12RB2: A Novel Animal Model for Generation of IL12 Therapies

AACR 2022: Evaluation of Therapeutic Drug Candidates Using a Novel Humanized B-hCSF1/hCSF1R

AACR 2022: Evaluating In Vivo Efficacy of Anti-VSIG4 Antibodies in Humanized B-hVSIG4 Mice

AACR 2022: Identifying New Therapeutic Antibodies Using Knockout Mice Expressing Human Immunoglobulin Variable Domain Genes

AACR 2022: Evaluating In Vivo Efficacy of Peptide Vaccines in Humanized B-HLA-A2.1 Mice

AACR 2022: Humanized TROP2 Mice Provide a Preclinical Tool for the Evaluation of Therapeutic Drugs Targeting TROP2

AACR 2022: Humanized IL36R Mice Provide a Preclinical Tool for the Evaluation of Therapeutic Drugs Targeting IL36R

AACR 2022: Evaluating In Vivo Efficacy of Bi-Functional Fusion Protein Anti-PD-1-IL21 in Humanized B-hIL21R Mice and B-hPD-1/hIL21R Mice

AACR 2022: Generation and Validation of Humanized GARP Mice for Testing Novel Anti-Human GARP Antibodies

AACR 2022: Humanized PVRIG Mice: A Novel Tool for Evaluating Anti-PVRIG Immunotherapies

AACR 2022: Functional Analysis of Anti-TSLP Antibodies Using Humanized B-hTSLP/hTSLPR Mice

AACR 2022: A Humanized Mouse Model of the Promising Immune Checkpoint Molecule B7-H4

AACR 2022: Generation of a Novel Humanized TLR8 Mouse Model for the Evaluation of Human TLR8 Agonists and Antibody-Conjugated TLR8 Agonists

AACR 2022: Advancing the Development of CD16A-Based Bispecific Antibodies in Humanized CD16A Mouse Models

AACR 2022: 1C3, a Novel Non-blocking Anti-human TNFR2 Antibody Generated From RenMice

AACR 2022: Generation of TCR-mimic fully human antibodies against HLA-antigen-peptide complexes using HLA transgenic RenMice

AACR 2022: YH012, a Novel Bispecific Anti-HER2 and TROP2 Antibody-Drug Conjugate, Exhibits Potent Antitumor Efficacy

B-hCD3E/hCD38 mice

B-hCD80 mice

B-hTEK mice

B-Epor-EGFP-iCre mice

B-hCCL2 MC38

B-Tg(mAger) MC38

B-Tg(mCd30l) MC38

B-Tg(mCcl2) MC38

B-Tg(mArtn) MC38

B-Tg(mEfemp1) MC38

B-Tg(mTff1) MC38

B-hBAFFR mice

B-hBAFF mice

B-hCD147 mice

B-NDG hFcRn mice

B-hCCL2 mice

B-hLRRC15 mice

B-hPD-1/hPD-L1/hIL1B mice

B-hIFNGR1/hIFNG mice

B-hCD55 mice

B-hCCR7 mice

B-Luc Hep 3B plus

B-hCCN2 mice

B-hLIGHT mice

B-hCD3EDG/hCD20 mice

B-Cdh5-iCreERT2 mice

B-hCD180 mice

B-hCD38-Luc E.G7-OVA

B-hCLDN18.2 BxPC-3

B-hIL27/hIL27RA mice

B-Tg(hCCL1) MC38

B-hTPBG B16-F10

B-Luc-EGFP MV-4-11

B-Luc-EGFP HL-60

RenLite共轻链抗体鼠与双靶点ADC药物开发案例

B-hC5AR2 mice

B-hHER2 mice

B-hAMHR2 MC38

B-CAG-iCreERT2 mice

B-hNKP46 mice

B-hTGM2 mice

B-hLAIR1-luc EL4

B-hSELP mice

B-hGPRC5D mice

B-hGPRC5D MC38

B-hPSMA MC38

B-hLILRB4 luc EL4

双抗ADC技术平台

抗体药物的体外药理分析方法与案例分享

B-hTREM2 mice

B16-F10-OVA

B-hCCR4-luc EL4

B-hSIGLEC15 mice

抗体药临床前药理学PK/PD分析

B-hCD98HC mice

B-hTLR2 mice

B-hIL11 mice

B-hIL27 mice

B-hCLDN6 MC38

B-hIL10/hIL10RA mice

靶向TAA免疫治疗药物临床前动物模型选择及药物评估

B-hCD89 mice

B-NDG B2m plus/hIL15 mice

B-hCD20 mice

B-hSIGLEC8 mice

B-hCD200R mice

B-hCD200 mice

B-hITGA5 mice

B-hPAI1 mice

B-hANGPTL4 mice

B-hCCN1 mice

B-hB7-H3 CT26.WT

B-hMSLN mice

B-hPSCA mice

B-hSRB1 mice

代谢疾病药物开发中的动物模型选择

B-hIL15RA mice

B-hIL7R mice

B-CAG-iCre rats

B-hIL10RB mice

B-hCD36 MC38

B-hC5/hC5AR1 mice

B-Igh-J KO mice(C)

B-hIL11RA mice

B-hIL36R mice

B-NDG Hc mice

B-hIL36A mice

B-hCCR9 mice

B-hCD73/hCD39 mice

B-hIFNGR2 mice

B-hTGFBR2 mice

B-h4-1BB/hCD27 mice

B-hTREM1 mice

B-hCXCR4 mice

B-hCSF1 mice

B-hCD2 mice

B-hIL17RA mice

B-NDG小鼠

B-NDG免疫缺陷鼠+人免疫细胞重建

自发型肿瘤模型

野生型小鼠+TAA人源化细胞系

靶点人源化小鼠+野生型/人源化细胞系

炎症性肠炎( IBD)模型

IBD小鼠疾病模型用于评价炎症性肠炎药物环孢菌素A（Ciclosporin A, CsA）的药效

实验性自身免疫脑脊髓炎（EAE）模型

EAE小鼠模型的构建

相关产品列表

哮喘（Asthma）模型

OVA诱导的哮喘小鼠（C57BL/6）模型的构建及验证

哮喘小鼠模型（BALB/c）用于评价皮质类固醇类免疫抑制剂地塞米松的药效

哮喘小鼠模型（B-hIL4/hIL4RA）用于评价抗人IL4RA抗体药物dupilumab的药效

相关产品列表

银屑病小鼠模型

小鼠疾病模型的建立

银屑病小鼠疾病模型用于评价地塞米松（DXM）药效

B-hIL17A/hIL17F小鼠银屑病模型用于评价抗人IL17A/IL17F 抗体药效

相关产品列表

胶原诱导型关节炎（CIA）疾病模型

小鼠疾病模型的建立

C57BL/6小鼠关节炎模型用于评价氨甲喋呤（MTX）药效

高脂肪蛋氨酸胆碱缺乏饮食(HFMCD)诱导的NASH小鼠模型

B-hIL6/hIL6R小鼠关节炎模型用于评价抗人IL6抗体sirukumab药效

非酒精性脂肪性肝炎（NASH）模型介绍

相关产品列表

特应性皮炎（AD）模型

AD小鼠模型的构建

AD小鼠疾病模型用于关节炎药物药效评价的实例

西方饮食(WD)诱导的NASH小鼠模型构建

自免疾病药物爆发，如何选择动物模型加快产品布局

靶向NK细胞肿瘤免疫治疗药物临床前药效动物模型的选择及药效评估

B-hFGL1 MC38

B-hMERTK mice

B-hGAS6 mice

B-hTROP2 mice

B-hAXL mice

B-hCXCR4 MC38

B-Luc LLC1

B-hNECTIN4 MC38

B-hCD155 MC38

B-hSIRPA/hCD47/hCD3E mice

B-hCD28/hB7-H3 mice

B-hITGB7 mice

B-hIL3 mice

B-hGPC3 mice

B-hHER2 MC38

B-hCD70 mice

B-hIL27RA mice

B-hIL9R mice

B-PD-1-EGFP KI mice

B-hANGPTL8 mice

B-hAMHR2 mice

B-hCD63 mice

B-hCD44 mice

B-hCD4 mice

B-hCX3CR1 mice

肿瘤免疫治疗逆转T细胞耗竭及调控

人免疫系统重建模型的构建和应用

2021年

B-hCB1 mice

B-hIGFBP2 mice

B-hTROP2 MC38 plus

B-hDLL3 MC38

B-hCD39 mice

B-hGARP mice

B-hROBO4 mice

B-hFN14 MC38

B-hPD-L1 MC38

B-hMCAM mice

B-hLILRB4 MC38

B-hB7-H4 B16-F10

B-hCD19 EL4

B-hPD-L1 low B16-F10

B-hHER2 EL4

B-hB7-H3 EL4

B-hCLDN18.2 A549

B-hEPCAM EL4

B-hCD20 EL4

B-hPD-L1 Raji-luc

B-hPD-L1 EL4

B-hCD47 CT26.WT

B-hPD-L1 B16-F10

B-hPD-L1 LLC1

B-luc A20

B-luc Daudi

B-luc EL4

B-luc B16-F10

B-luc MIA PaCa-2

B-luc K-562

B-luc-GFP Raji

B-hCD16A mice(CB-17 SCID)

解密RenLite-抗体世界里的灵魂相依

B-hCD16A mice

B-hSOST mice

B-hITGAV mice

B-FcRn KO mice

B-hPCSK9 mice

B-Rag2 KO mice

B-NDG-mice

B-hNTRK1 mice

B-hCXCR5 MC38

B-hTF MC38

B-hIL17RB mice

B-hCD24 MC38

B-hSPP1 mice

B-hCD37 MC38

B-hFAP MC38

B-hCD37 mice

B-hPVRIG mice

B-hC5 MC38

B-hCD248 mice

B-hMERTK MC38

B-hIL1RAcP mice

B-hPSMA mice

B-hCD93 mice

B-hPD-L1 plus/hCEA MC38

B-hCD38 MC38

B-hCLDN18.2 MC38

B-hCD19 MC38

B-hBCMA mice

B-hVSIG4 mice

B-hPDPN mice

B-hB7-H4 mice

B-hCD36 mice

B-hCD43 mice

B-hITGB1 mice

B-Tgfb1 cKO mice

B-ROSA26-EGFP-DTA mice

B-IL17a-EGFP mice

B-CAG-tdTomato cKI mice

B-Oxt-iCre rats

B-Drd2-Cre rats

B-Camk2a-iCre-EGFP mice

B-Cx3cr1-iCreERT2-EGFP mice

B-Pgr-iCre mice

B-Tagln-iCre mice

B-Gfap-iCre mice

B-Tcf21-iCreERT2 mice

B-Htr2c-iCre mice

B-Ucp1-iCre mice

B-Sp7-iCre mice

B-Prrx1-iCre mice

B-Pdgfrb-iCre mice

B-Nkp46-iCre mice

B-Grpr-iCre mice

B-mSiglec15 MC38

B-HLA-E MC38 plus

B-hTPBG MC38

B-hSIGLEC15 MC38

B-hCXCR2 MC38

B-hB7-H4 MC38

炎症性肠病( IBD)模型

B-hCD39 MC38

B-hCCR4 MC38

B-hPD-L1 low MC38

B-hROR1 MC38

B-hCD73 MC38

B-hTNFR2 MC38

B-hBCMA MC38

B-hCD20 MC38

B-hEPCAM MC38

B-hB7-H3 MC38

B-hPD-L2 MC38

B-hCD47 MC38

B-hHVEM MC38

B-hCEACAM1 MC38

B-hCEACAM1 mice

B-hVEGFR2 mice

B-hPDGFRB mice

B-hGDF15 mice

B-hC5/hC5AR1 mice

B-hCD14 mice

TNFR2 and PD-1/PD-L1/TNFR2 humanized mice aiding exploration of combination strategies to overcome tumor immune escape mechanisms

Double-humanized 4-1BB/4-1BBL mouse is an advanced model for liver toxicity and efficacy evaluation of 4-1BB therapeutic antibodies

Improved LAG-3 humanized knock-in mouse model for assessment of mono- and combination therapy strategies for cancer treatment

Advancing Bispecific Antibody Discovery using a Common Light Chain Immunoglobulin Humanized Mouse

A novel humanized B-hPD-1/hPD-L1/hTIGIT mouse model reveals enhanced efficacy of combined TIGIT and PD-L1 blockade against cancer

Human CD73 knock-in mice facilitate evaluation of in vivo efficacy of anti-human CD73 cancer immunotherapies

Novel Engineered B-NDG B2M KO Mice Plus Shows Delayed GvHD response and Favorable GvL Immune Profiling After hPBMC Engraftment

Novel human B7-H3 knock-in mice demonstrate efficacy of anti-B7-H3 immunotherapy in vivo

Humanized IL17A/IL17F mouse model provides a preclinical tool for the evaluation of therapeutic drugs targeting to IL-17 pathway

Evaluating anti-SIRPα in vivo efficacy in humanized B-NDG hSIRPA mice and B-NDG hSIRPA/hCD47 mice

Anti-GCGR in vivo efficacy evaluated in a new humanized hGCGR mouse model

Humanized IL6/hIL6R mouse model supports the evaluation of therapeutic drug candidates targeting human IL6 and IL6 receptor

Humanized B-hC5AR1 mouse model for evaluation of anti-C5AR1 mAb in vivo efficacy

Humanized CCR8 Mouse Model Provides A Translational Tool For Anti-Human CCR8 Antibody Drug Development

SIGLEC15 humanized knock-in mice are a powerful tool to evaluate new therapies for cancer and osteoporosis

A Novel PD1-CD40 Bispecific Antibody YH008 Induces Potent Anti-tumor Activity in-vivo by PD1 Dependent Activation of CD40 Signaling

B-hCXCR5 mice

B-hCALCRL mice

B-hPSGL-1 mice

B-hCD45 mice

B-hCD155 mice

B-hCCR6 mice

B-hIFNGR1 mice

B-hITGA4 mice

B-hRSPO1 mice

西方饮食(WD)诱导的NASH小鼠模型

四氯化碳(CCl4)诱导肝纤维化和肝硬化的NASH小鼠模型

HFMCD诱导的NASH模型

银屑病小鼠模型

哮喘（Asthma）模型

多发性硬化（MS）模型

类风湿性关节炎（RA）疾病模型

B-hFGL1 mice

B-hCXCL13 mice

B-hCD5 mice

B-hCSF2RB mice

B-hRANKL mice

B-hRAGE mice

B-hCD52 mice

B-hA2AR mice

B-hTIM3 mice

B-hLRRC33 mice

B-hCCR2 mice

B-hGCGR mice

基因编辑技术在新药研发中的应用与进展

B-hCCR5 mice

B-hIL1B mice

B-hIL7R mice

B-hTFR1 mice

B-hTNFR2 mice

B-hTPBG mice

B-hCSF1R mice

B-hIL21R mice

B-hIL2RB mice

B-hIL2RG mice

B-hIL2 mice

B-hIL2RA mice

B-hIL10 mice

B-hIL13 mice

全人抗体发现与分析

B-hTIM4 mice

B-hCD33 mice

B-hCD22 mice

B-hCD40L mice

B-hCD47 mice(C)

B-HLA-A2.1 mice

B-hTLR8 mice

B-hIL33 mice

B-hCD79B mice

B-hSIGLEC10 mice

B-hTLR9 mice

B-hIL10RA mice

B-hVSIR mice

B-hCD94 mice

B-hCD73 mice

B-hLAG3 mice plus

B-hNKG2A mice

B-dPD-1 mice

B-hPD-1 mice plus

B-hTIGIT mice

B-hSIRPA mice

B-hOX40 mice

B-hPD-L1 mice

B-hGITR mice

B-hCTLA4 mice

B-hB7-H3 mice

B-hCD28 mice

B-hCD226 mice

B-hIL17A mice​

B-hTNFA mice

B-NDG mice 免疫重建模型+CDX

B-hGLP1R mice

B-hCXCR2 mice

B-hETAR mice

B-hCCR4 mice

B-hCCR8 mice

小鼠免疫缺陷系统CDX模型

B-hC5AR1 mice

2020年

2019年

2018年

2016年

2015年

2014年

2011年

GPCR技术平台

B-h4-1BB mice

B-hPD-1 mice

百奥大学

Gene Editing

基因编辑

千鼠万抗

强强联合 加速新药开发

2009

B-hBTLA mice

BCG004

B-hCD40 mice

B-hCD3E mice

B-hCD27 mice

B-hCD47 mice

B-hPD-L1 MC38 plus

特应性皮炎（AD）模型

II型糖尿病模型

双抗技术平台

类TCR（TCRm）抗体技术

药物临床开发

大动物转化医学

临床前药理药效评价

【人才汇聚】百奥赛图获批设立博士后科研工作站

促销成团之夜--见证B-NDG小鼠高光时刻！

百奥赛图与君实生物达成关于RenMab小鼠授权使用的合作

全人抗体发现与分析

公司年会

公司团建

战略研讨会

RenMice

RenMice

The Infectivity and Antigenicity of Epidemic SARS-CoV-2 Variants in the United Kingdom

Cross-Neutralizing Activity of Monoclonal Antibodies Against N501Y Mutant Strain of SARS-CoV-2

百奥赛图携手维亚生物，就共同加速新药早期研发达成战略合作

百奥赛图与国药集团中国生物上海生物制品研究所签署全人抗体合作开发协议

Selective optogenetic activation of orexinergic terminals in the basal forebrain and locus coeruleus promotes emergence from isoflurane anaesthesia in rats

B-NDG及二代产品小鼠在肿瘤免疫中的应用

Efficient Strategies for Microglia Replacement in the Central Nervous System

The establishment of humanized IL-4 IL-4RA mouse model

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

自身免疫性疾病-动物模型选择及药物开发应用

抗体药物开发的陷阱及对策

利用人源化小鼠模型评估抗体药PK/PD及安全性

肿瘤免疫2.0时代-双抗，多抗联用策略及临床前动物模型选择

In Vivo vs. In Vitro Therapeutic Antibody Discovery；Evolution, Differentiation and More

RenMab Mouse: A Leading Platform for Fully Human Antibody Generation

Rapid screening of novel OX40 agonistic antibodies for cancer immunotherapy

Novel TNFR2 humanized mouse model for human TNFR2 antibody evaluation

Long-term Maintenance of Human Mature NK Cells from hCD34+HSCs Engraftment Supported by Immune Humanized B-NDG hIL15 Mice

In vivo drug screening platform accelerates anti-hCD40 antibody drug discovery

Immune Biomarker Profiling and Safety Evaluation Response to 4-1BB Antibody (Urelumab) in Humanized 4-1BB Mice

Evaluating anti-PD-1/4-1BB combination therapy: In vivo efficacy with humanized double knock-in mice

Evaluating Anti-IL-2Ra in vivo Efficacy on Humanized Knock-in Mice

Efficacy Evaluation of Bispecific Antibodies in Humanized Mice after B Cell Depletion

Development of A Novel Engineered B2M Mouse Strain on B-NDG Background hat Specifically Eliminates MHC I Expression While Retaining Normal

A novel anti-CTLA-4 antibody with potent anti-tumor activity emerged using humanized CTLA-4 mouse model

Optimization of novel anti-4-1BB antibodies on Biocytogen’s in vivodrug screening platform

Novel CD3e humanized mouse models for preclinical pharmacology study of therapeutic bispecific antibody

Novel IL4/IL4RA double humanized mouse models for in vivo efficacy evaluation of human IL4 and human IL4RA antibodies in asthma models

Using humanzied B-hSIRPa/hCD47 mouse model to evaluate the efficacy and toxicity of CD47 and SIRPa antibodies

Rapid screening of anti-OX40 antibodies for cancer immunotherapy

Novel CTLA4 antibodies of potent antitumor activity were verified in humanized mouse models

Human immune system reconstituted B-NDG mouse models are ideal tools for CAR-T and therapeutic antibody preclinical efficacy evaluation

Evaluating anti-PD-1/CD40 in vivo efficacy and saftey on humanizied double knock-in mice

Novel hCD3e mouse models for preclinical pharmacology studies of therapeutic bi-specific antibodies

Novel in vivo durg screening platform accelerated 4-1BB agonistic antibody development

Anti-SIRPα antibodies as a potential weapon for cancer immunotherapy via accelerated screening in humanizied mouse models

Novel anti-CD40 antibodies demonstrate anti-tumor activity in humanized mouse models

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