SIGLEC-15 Blocking Antibody (BCG008)

Asset ID: BCG008
Targets: SIGLEC-15
  • Aliases:
  • CD33L3, HsT1361
  • Modality:
  • Fully human monoclonal antibody (mAb)
  • Development Stage:
  • Phase I (China)
  • Indications:
  • Pan-cancer; monotherapy and combination immunotherapy, including anti-PD-L1 combinations
  • Key Differentiation:
  • High-affinity SIGLEC-15 blockade with a distinct epitope, human/cynomolgus cross-reactivity, favorable preclinical efficacy and safety, and flexibility for monotherapy or combination immunotherapy
  • Partnership Opportunity:
  • Available for ex-China licensing and co-development
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