B-hCCL22 mice

C57BL/6-Ccl22tm1(CCL22)Bcgen/Bcgen • 110817

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B-hCCL22 mice

Catalog Number: 110817
Strain Name: C57BL/6-Ccl22tm1(CCL22)Bcgen/Bcgen
Strain Background: C57BL/6
NCBI gene ID: 6367 (Human)
Aliases: MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1
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B-hCCL22 mice

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  • Phenotypic analysis

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      mRNA expression analysis
      Strain specific analysis of CCL22 gene expression in wild type (WT) mice and B-hCCL22 mice by RT-PCR.Mouse Ccl22 mRNA was detectable only in thymus of WT mice (+/+). Human CCL22 mRNA was detectable only in homozygous B-hCCL22 mice (H/H) but not in WT mice (+/+).
      Protein expression analysis
      Strain specific CCL22 expression analysis in wild type (WT) mice and B-hCCL22 mice by ELISA.Thymus homogenates were collected from WT mice (+/+) and homozygous B-hCCL22 mice (H/H), and analyzed by ELISA with species-specific CCL22 ELISA kit. Mouse CCL22 was detectable in WT mice. Human CCL22 was exclusively detectable in homozygous B-hCCL22 mice (H/H) but not WT mice (+/+) . Values are expressed as mean ± SEM. ND: not detectable.
      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hCCL22 mice] (Cat# 110817) was purchased from Biocytogen.