B-hIL18 mice

C57BL/6N-Il18tm2(IL18)Bcgen/Bcgen • 111276

获取报价

B-hIL18 mice

Catalog Number: 111276
Strain Name: C57BL/6N-Il18tm2(IL18)Bcgen/Bcgen
Strain Background: C57BL/6N
NCBI gene ID: 3606 (Human)
Aliases: IGIF; IL-18; IL-1g; IL1F4
---
可提供授权方案
获取报价
B-hIL18 mice

在此页面上

  • Targeting strategy
  • Phenotypic analysis

海报

查看全部

    发表文章

      相关产品

      查看全部
      Targeting strategy

      Gene targeting strategy for B-hIL18 mice. The exons 2-6 of mouse Il18 gene that encode the full-length protein were replaced by human IL18 exons 2-6 in B-hIL18 mice.

      Protein expression analysis

      Strain specific IL18 expression analysis in homozygous B-hIL18 mice by ELISA. Serum were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL18 mice (H/H), and analyzed by ELISA with species-specific IL18 ELISA kit. Mouse IL18 was detectable in wild-type mice. Human IL18 was exclusively detectable in homozygous B-hIL18 mice but not in wild-type mice.

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hIL18 mice] (Cat# 111276) was purchased from Biocytogen.