Protein expression analysis
Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Splenocytes were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was detectable in wild-type mice. Human NKP46 was exclusively detectable in homozygous B-hNKP46 mice(C).
Protein expression analysis in T and B cells of spleen
Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Splenocytes were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was not detectable in T and B cells of wild-type mice. Human NKP46 was not detectable in T and B cells of homozygous B-hNKP46 mice(C).
Protein expression analysis in blood
Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Blood cells were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was detectable in wild-type mice. Human NKP46 was exclusively detectable in homozygous B-hNKP46 mice(C).
Protein expression analysis in T and B cells of blood
Strain specific NKP46 expression analysis in wild-type and B-hNKP46 mice(C) by flow cytometry. Blood cells were collected from BALB/c (+/+) and homozygous B-hNKP46 mice(C) (H/H), and analyzed by flow cytometry with species-specific NKP46 antibodies. Mouse NKP46 was not detectable in T and B cells of wild-type mice. Human NKP46 was not detectable in T and B cells of homozygous B-hNKP46 mice(C).
* When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hNKP46 mice(C)] (Cat# 112004) was purchased from Biocytogen.
