B-hPDPN mice

C57BL/6N-Pdpntm1(PDPN)Bcgen/Bcgen • 111099

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B-hPDPN mice

Catalog Number: 111099
Strain Name: C57BL/6N-Pdpntm1(PDPN)Bcgen/Bcgen
Strain Background: C57BL/6N
NCBI gene ID: 10630 (Human)
Aliases: T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; D2-40; T1A-2; AGGRUS; HT1A-1; PA2.26
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B-hPDPN mice

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  • Phenotypic analysis

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      Protein expression analysis
      Strain specific PDPN expression analysis in homozygous B-hPDPN mice by western blot. Lung tissue was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hPDPN mice (H/H), and analyzed by western blot with anti-PDPN antibody. Mouse PDPN was only detectable in wild-type C57BL/6 mice. Human PDPN was only detectable in homozygous B-hPDPN mice but not in wild type mice.
      mRNA expression analysis
      Strain specific analysis of PDPN gene expression in wild-type C57BL/6 mice and B-hPDPN mice by RT-PCR. Mouse Pdpn mRNA was detectable in brain of wild-type C57BL/6 mice (+/+). Human PDPN mRNA was detectable only in homozygous B-hPDPN mice (H/H) but not in wild type mice.
      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hPDPN mice] (Cat# 111099) was purchased from Biocytogen.