B-hTNFA/hTNFR2/hTNFR1/hIL23A/hIL12B mice were obtained by mating B-hTNFA/hTNFR2/hTNFR1 mice (131706) and B-hIL23A/hIL12B mice (120553). For validation data of this mouse model, you can refer to the validation data from the related gene humanized mouse models.