B-NDG hB2M/HLA-A3.1 mice

NOD.CB17-PrkdcscidIl2rgtm1BcgenB2mtm1(B2M/HLA-A3.1)Bcgen/Bcgen • 112450

订购产品
B-NDG hB2M/HLA-A24.2 mice plus
B-NDG hB2M/HLA-A3.1 mice plus

B-NDG hB2M/HLA-A3.1 mice

Product nameB-NDG hB2M/HLA-A3.1 mice
Catalog number112450
Strain nameNOD.CB17-PrkdcscidIl2rgtm1BcgenB2mtm1(B2M/HLA-A3.1)Bcgen/Bcgen
Strain backgroundB-NDG
NCBI gene ID5591,3561,567,3105 (Human)
AliasesDNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350; CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1; IMD43; HLAA
ApplicationTo verify the efficacy of HLA-A3.1 restricted vaccines and antibody-based therapies；Promote the development of human CD8+ T cells
订购产品

在此页面上

  • Phenotypic analysis

海报

查看全部

    发表文章

      Protein expression analysis
      B2M and HLA-A3.1 expression analysis in homozygous B-NDG hB2M/HLA-A3.1 mice by flow cytometry. Splenocytes were collected from B-NDG mice (+/+) and homozygous B-NDG hB2M/HLA-A3.1 mice (H/H), and analyzed by flow cytometry with strain specific antibodies. Mouse B2M was detectable in B-NDG mice but not in B-NDG hB2M/HLA-A3.1 mice. Human B2M and HLA-A3 were exclusively detectable in homozygous B-NDG hB2M/HLA-A3.1 mice but not in B-NDG mice.