Interleukin 6 (IL-6) gene encodes a cytokine that functions in inflammation and the maturation of B cells and is a potent pleiotropic
cytokine that regulates cell growth and differentiation and plays an important role in the immune response Evidence of recent
research shows blockade of IL-6 and IL-6 receptor interaction can offer a broader therapeutic strategy for various diseases included
in acute systemic and chronic inflammatory diseases. The development of humanized mouse model can greatly support preclinical
evaluation of human IL6 and IL6 receptor therapeutic drugs.
